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GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Finasteride's sexual side effects not caused by androgen deficiency or SRD5A inhibition.

Testosterone increases hamster hair growth; cyproterone acetate reduces it.

Male hormones can decrease the ability of immune cells to fight bacteria.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

New finasteride solution effectively reduces baldness-causing hormone, potentially with fewer side effects.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

Spironolactone reduces the number of androgen receptor sites in rat skin by blocking them with its metabolite.

PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

RU58841, a substance from France, can potentially block the effects of hormones that cause hair loss and excessive hair growth, performing better than a similar substance, cyproterone acetate.

The research found that androgens help control blood flow in the rat prostate through a specific binding site.

A new treatment for hair loss shows promise with fewer side effects.

Higher levels of heat shock protein 27 and lower levels of miR-1 can increase AR levels, leading to hair loss in men.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.

Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.

The new compound was more effective than finasteride in reducing markers of hair loss and prostate issues in cell tests.

BMPs are important for hair growth and can counteract the negative effects of androgens on hair follicle stem cells.

Minocycline may cause hair loss by increasing DHT levels, but finasteride can help counteract this effect.

The research helps understand how finasteride works and aids drug development.

Blocking the enzyme that turns testosterone into DHT can safely and effectively treat enlarged prostate.

New A-homo-B, 19-dinor steroids showed strong antiandrogenic activity without affecting the enzyme 5α-reductase or androgen receptor binding.

Carbamates may help treat androgen-dependent conditions by changing how certain lipid enzymes are produced.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Compounds from the Sansevieria trifasciata plant might be effective for treating hair loss.