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Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Rice bran extract might help prevent hair loss.

Finasteride may improve prostate cancer treatment outcomes.

Ganoderma lucidum may help treat prostate cancer by blocking male hormones and slowing cancer cell growth.

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

Finasteride helps treat hair loss by blocking enzyme activity.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Monascus helps prevent baldness, prostate issues, and may be a natural alternative to medications.

Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Anti-androgens are effective for female acne but less so for male-pattern hair loss, with side effects similar to birth control pills.

Scientists at the University of Michigan Medical School successfully created a special compound that can be used to improve imaging of prostate cancer.

Active oxygen scavengers can reverse the suppression of hair cell growth caused by androgens.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Sebocytes play a key role in controlling androgen levels in human skin.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Too much androgen can cause hair loss; finasteride may help.

Finasteride effectively blocks enzyme causing male pattern baldness.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Male pattern baldness involves hormones and cell signals affecting hair growth.

Finasteride effectively blocks rat enzymes, but with varying methods and strength.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.