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Too much male hormone in mothers can negatively affect the sexual behavior of both male and female baby mice.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might reduce it. AST decreases recurrence-free survival but doesn't affect overall survival or progression-free survival. More research is needed to understand AST's benefits.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might decrease the risk. AST also lessens the chance of cancer coming back but doesn't really affect survival rates. More research is needed to understand AST's benefits for different bladder cancers.

Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.

Finasteride may cause lasting sexual and mental health issues, and genetic screening could help prevent them.

Best results found using acetonitrile, water, and trifluoroacetic acid or methanol mixture.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Blocking a specific enzyme in male rat fetuses leads to the development of nipples and feminized genitalia.

Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Longer TA repeats in the SRD5A2 gene may increase acne risk in Chinese people.

A new method was developed to make finasteride for treating hair loss.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

These drugs cause hair growth without affecting testosterone or adrenal hormones.

The study found that urine metabolites M1b or M4 are the best indicators of ATD use in horses, with detection possible up to 77 hours in urine and 28 hours in blood.

Giant cells found in some male pattern baldness cases may help diagnose it and suggest hair is mistakenly seen as foreign by the body.

Venous catheterization may help diagnose the cause of female hyperandrogenism when imaging is unclear.

BRL 7660, once studied for male contraception, showed promise as an acne treatment but was not developed further due to competing drugs.

Free fatty acids may increase androgen production, potentially contributing to polycystic ovary syndrome.

Alopecia X in dogs is a cosmetic issue, not a hormonal disorder, and harmful treatments should be avoided.

Four-amino acid part makes enzyme sensitive to finasteride.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.

Red deer only have androgen receptors in neck hair cells for mane growth during breeding season.

Better hair loss models needed for research.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.