1 citations
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July 1991 in “PubMed” This case report describes a patient with adrenomyeloneuropathy, highlighting unusual MRI findings of high signal areas in the right striatum.
56 citations
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December 2011 in “The Plant Journal” AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.
69 citations
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May 2009 in “Journal of Investigative Dermatology” This research highlights that psychological stress can adversely affect hair growth in mice, implicating potential pathways that may be relevant in understanding stress-induced hair growth inhibition in humans.
9 citations
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January 2005 in “Experimental Dermatology” This study found that human hair follicles can function like a peripheral hypothalamic-pituitary-adrenal axis, synthesizing cortisol in response to corticotropin-releasing hormone and adrenocorticotropic hormone stimulation.
40 citations
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February 2013 in “American Journal of Clinical Dermatology” This study found that people with androgenic alopecia, particularly women, are more prone to anxiety and depression, often adopting avoidant coping strategies, which are linked to emotional and psychological impacts rather than clinical severity.
5 citations
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June 2010 in “Universitas Psychologica” This study found that progesterone implantation in castrated male rats mitigated stress-induced increases in corticosterone levels and protected against spatial memory impairment and increased exploratory behavior.
November 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study found that patients with androgenetic alopecia experience significantly higher symptoms of anxiety, depression, stress, and body image dissatisfaction compared to non-AGA controls, along with generally reduced self-esteem and life satisfaction.
May 2024 in “Brain disorders” In this animal study, agmatine exhibited a protective effect against seizures related to hormone fluctuations, with results suggesting that its anticonvulsant properties may involve interactions with central neurosteroids in female rats experiencing progesterone withdrawal.
21 citations
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May 2016 in “Progress in Neuro-Psychopharmacology and Biological Psychiatry” Diazepam's effects on anxiety and memory differ between male and female rats due to hormonal influences.
May 2024 in “International journal of medicine and psychology.” This study highlights the importance of creating targeted psychological support activities for war veterans, as the findings suggest these interventions can help correct maladaptive behaviors and enhance stress coping strategies, ultimately aiding veterans in their rehabilitation and social adaptation.
293 citations
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November 2005 in “Trends in Immunology” This study indicates that stress in mice recruits specific neuroimmunoendocrine elements, leading to neurogenic skin inflammation that inhibits hair growth and highlights the skin's role in stress response research.
August 2018 in “Brock University Digital Repository (Brock University)” This study suggests that the elevated stress hormone response in adolescent male rats may involve increased conversion of testosterone to estradiol at the adrenal cortex level.
43 citations
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October 2005 in “Molecular and cellular endocrinology” This review discusses how the CRH/POMC systems may regulate human hair follicle pigmentation and highlights the concept of "self-similarity" in melanocortin systems at both local and systemic levels, without presenting new experimental results.
25 citations
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June 2017 in “Neuropharmacology” This study observed that overexpressing TSPO in the hippocampal dentate gyrus of mice led to significant anxiolytic and antidepressant-like effects, potentially mediated by increased allopregnanolone synthesis.
43 citations
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May 1999 in “Journal of Biological Chemistry” This study found that full-length Agouti protein modulates melanocortin receptor signaling through a dual mechanism involving competitive antagonism and receptor down-regulation, whereas the carboxyl-terminal fragment acts solely as a competitive antagonist.
February 2024 in “Psychoneuroendocrinology” In this study, researchers found that higher levels of general and pregnancy-related anxiety during gestation were negatively correlated with neonatal hair cortisol levels, suggesting that increased maternal anxiety may alter fetal cortisol exposure, which is important for fetal development.
January 2026 in “International Journal of Clinical Practice” This study found that individuals with alopecia areata have higher levels of anxiety and depression compared to healthy individuals, with longer disease duration linked to increased anxiety and severe severity predicting higher depression.
12 citations
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June 2019 in “Psychoneuroendocrinology” This study found that in rodent models, the ability of D1 dopamine receptor activation to impair sensory gating is facilitated by 5α-reductase type 1, which produces allopregnanolone.
November 2025 in “Skin Health and Disease” This study found that patients with alopecia areata had a higher prevalence of depression, anxiety, and alexithymia compared to normative data, with alexithymia more common in those with earlier onset AA, lower education levels, and younger age.
This study found that the attractiveness of women's faces had a significant but weak effect on negative emotions among participants, while website background color influenced positive emotions with green being preferred.
June 2025 in “British Journal of Dermatology” This study introduces ALUDWIG, an automated tool for assessing female androgenic alopecia severity from smartphone images, which may offer a more consistent alternative to current scoring methods like the Ludwig scale.
April 2024 in “JOURNAL OF Mental Health Concerns” This study observed that self-affirmation therapy significantly reduced anxiety levels in students before they carried out structured presentation tasks, as indicated by statistical analysis showing a p-value of 0.000.
4 citations
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October 2017 in “Journal of Mind and Medical Sciences” This overview discusses the mind-body problem and suggests that the brain may be intrinsically part of the mind, processing abstract data without direct interaction, but reports no new research results.
February 2024 in “Psychoneuroendocrinology” This study observed that higher anxiety levels in pregnant individuals are negatively correlated with neonatal hair cortisol, suggesting that increased anxiety during pregnancy may affect fetal cortisol accumulation, which is important for fetal development and associated with birth outcomes and cognitive function.
March 2026 in “International Journal of Health Science” This review discusses the emotional impact of androgenetic alopecia and emphasizes the importance of integrating emotional support into dermatological nursing care to improve patient outcomes.
15 citations
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February 2000 in “Journal of Cutaneous Pathology” This study suggests that the anchorage of the arrector pili muscle to the extracellular matrix is likely mediated by α5β1 integrin, with α1β1 integrin involved in muscle cell-cell adhesion.
1 citations
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June 2011 in “대한구강악안면외과학회지” This case study reports an epidermoid cyst diagnosis in a woman who developed swelling in the left parotid gland following botulinum toxin injection in the left masseter muscles.
November 2021 in “Frontiers in Genetics” This study found that a new FAW-FS algorithm improved recognition of depression in patients with androgenic alopecia, and comprehensive psychological interventions positively impacted their rehabilitation outcomes.
2 citations
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September 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study demonstrated that ablation of individual somatostatin-expressing interneurons increased activity in nearby neurons of the mouse motor cortex during motor learning.
173 citations
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November 2004 in “Seminars in Reproductive Medicine” This review discusses the physiological process of adrenarche, its impact on behavior and skeletal maturation, and its variability across sex and race, but reports no new clinical results.