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This article reviews the regulation and roles of spermidine/spermine-N(1)-acetyltransferase (SSAT) in polyamine metabolism and its potential as a target in cancer and other diseases, without reporting new experimental results.

This review discusses the emerging role of AMT in fibrosis and suggests that targeting AMT could offer a novel approach to treatment; it reports no new clinical results.

This review explores the synthesis and potential of azasteroids as novel drugs, discussing challenges in their production and reporting no new clinical results.

This study found that early diagnosis using gas chromatography/mass spectrometry and appropriate long-term treatment are crucial for improving outcomes in patients with methylmalonic acidemia.

This case report details the diagnosis and management of argininosuccinate lyase deficiency in an infant, emphasizing initial symptoms, treatment strategies, and subsequent liver transplant leading to recovery.

In this study, researchers developed a coamorphous form of tadalafil and finasteride, showing improved solubility and dissolution in vitro, with results successfully translated in vivo in rats. They reported reasonable stability, suggesting this form could serve as a therapeutic alternative to the current marketed combination.

This study investigated the effects of ammonium thioglycolate and amino methylpropanol hair straightening followed by permanent coloring, finding significant physical and chemical changes to both the cuticle and cortex of hair fibers.

This study developed an advanced HPLC-ESI-ion trap MS(n) method for the structural identification of cyclosporin A analogs CyA and CyC and reported the first MS(n)-aided identification of a new CyA analog.

This study found that stilbamidine and hydroxystilbamidine can inhibit the release of specific enzymes from lysosomes and mitochondria in rabbit liver at certain concentrations, with effects similar to cortisol and chloroquine.

In this study, the combination of biologically engineered hyaluronic acid and polyquaternium-10 improved hyaluronic acid's retention and moisturizing effects on hair by forming a stable complex that increased binding affinity to keratin.

RADA16-I can effectively deliver and release mangiferin, improving its solubility and bioavailability.

This study synthesized indole-acenaphthylene compounds using a magnetic nanocatalyst and explored their photoluminescence properties for detecting copper ions in a mixed solvent system, achieving a detection limit of 9.5 ∙ 10 –6 M.

Metabolic disorders can cause hair structure defects and growth issues, but amino acid levels in hair remain normal.

Transamidases are present in the epidermis but their exact role is unclear.

This study found that chemically modifying human hair through esterification or disulfide reduction and alkylation affects the hair's viscoelastic properties, including stability, integrity, and response to moisture.

This study found that bioconjugating 16-methylheptadecanoic acid (16-MHA) to damaged hair can mimic the protective properties of 18-methyleicosanoic acid (18-MEA), restoring the hair's structural integrity and moisture homeostasis, even after washing.

In this study, researchers developed a novel delivery system using hyaluronic acid gels to encapsulate Huperzine A for Alzheimer's treatment, achieving extended release over 20 days and significantly improving pathology and behavior in mice, including enhanced memory and reduced neuroinflammation.

This study identified N-acyl arylsulfonamides, particularly N-(Boc-piperidine-4-carbonyl)-benzenesulfonamides, as steroid sulfatase inhibitors with improved cellular potency compared to previous compounds.

This study found that adding urea to a polyethyleneimine solution improved the coloring ability and color fastness of low-temperature hair dyeing with acid dye by enhancing dye penetration into the hair.

This study found that compound 3 derived from aza-bicyclo-carboxylic acid may exert a cardioprotective effect by reducing infarction area in myocardial ischemia-reperfusion injury, potentially involving A1-adenosine receptor activation and changes in cAMP levels.

In this study, researchers found that L-cysteine interacted electrostatically with anionic ions on the surface of keratin fibers in human hair, reducing the rate of disulfide bond disconnection at pH 9.0.

This case report details a 4-year-old girl with arginosuccinic-aciduria, showing neurological symptoms and weakened hair, but the mechanisms behind these issues remain uncertain.

This study found that PEGylated Ag₂S-ZnS@TGA-AA heteronanostructures, activated by light exposure, showed synergistic antibacterial effects against multidrug-resistant bacteria, significantly accelerating the healing of MRSA-infected wounds in comparison to untreated wounds.

In this study, researchers evaluated the binding of keratin-associated proteins and α-keratins to human hair fibers, finding that chemical preactivation significantly enhanced binding to natural hair, while perming altered binding characteristics and increased penetration depth.

This study found that hydrophilic carbon dots (Lys-CA-CDs) induced bovine serum albumin to form more wormlike fibrils, while inhibiting hen egg white lysozyme from forming hair-like fibrils.

This study found that sustained intracellular acidosis in mice was associated with shortened lifespan, early aging signs, and impaired autophagy.

In this study, researchers localized arginine and citrulline in rat hair follicles and found that arginine is abundant in trichohyalin droplets, while citrulline predominantly accumulates in the hardened inner sheath and medulla.

This study found that a specific amino-pyridine compound showed potent androgen receptor antagonist activity, stimulating hair growth in mice and reducing sebum production in a hamster model.

This study observed that hyaluronan's transformation into HA·3Ca and its hydrate increases drug absorption by changing its molecular characteristics, influenced by zwitterionic character and acidic pH.

This study found that subcutaneous injections of certain chelators led to skin and hair depigmentation, increased skin elasticity, and disturbed hair growth in minks, without affecting fur quality.