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The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

Herbs can potentially treat hair loss by inhibiting a key enzyme and promoting hair growth, and deficiencies in zinc, biotin, and iron are linked to hair loss.

Some men's prostate tissues have low enzyme levels due to genetic changes, possibly affecting treatment for prostate enlargement.

Some treatments like intralesional steroids and 5α-reductase inhibitors are effective for frontal fibrosing alopecia, but more research is needed.

Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.

An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.

The document concludes that Hidradenitis suppurativa is often underdiagnosed, lacks definitive treatment, and requires better awareness and management strategies.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.

Curcuma aeruginosa extract combined with minoxidil effectively treats male-pattern baldness.

Some herbs show promise as antiandrogenic agents.

Type I interferons play a key role in the development of various skin diseases.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

Some medications can reduce excessive hair growth in women, but more research is needed to find the best treatment combinations.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

Taking 5α-reductase inhibitors does not significantly increase the risk of breast cancer in men.

Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.

Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.

Finasteride potentially treats hair loss by reducing DHT production.

New compounds may soon be tested to treat excessive hair growth in women.

Undariopsis peterseniana extract helps hair grow by activating certain cell growth pathways and could be a new treatment for hair loss.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.

Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.