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Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Adding anti-Müllerian hormone to PCOS criteria lowers the number of women diagnosed.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

New effective scar treatments are urgently needed due to the current options' limited success.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Myrtle has various health benefits and potential for medicine development.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

New insights show Lichen Planopilaris is a rare, scarring hair loss condition, hard to treat, mainly affecting middle-aged women, and significantly impacts mental health.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Lichen planus is a skin condition that can resolve on its own, is linked to hepatitis C, and increases the risk of skin cancer.

Peptide hydrogels heal burn wounds faster and better than standard dressings.

Estrogen therapy can reduce skin aging but has cancer risks.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Stress can stop hair growth in mice, and treatments can reverse this effect.

Taking selenium supplements during chemotherapy may help reduce side effects and improve health markers in ovarian cancer patients.

Fat cells in the skin help start healing and form important repair cells after injury.