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Cyproterone acetate may cause liver cancer at high doses, but is considered safe at recommended doses for approved uses.

Alopecia areata treatment should be personalized, using topical or systemic therapies based on severity, with promising options like JAK inhibitors needing more research.

Xiangdong black goats have moderate genetic diversity, minimal inbreeding, and important genes for reproduction, immunity, and other traits.

Hibiscus has medicinal benefits but can be toxic in high doses and is unsafe for pregnant women and infants.

Scientists created a lab-grown hair follicle model that behaves like real hair and could improve hair loss treatment research.

Sunflower oil was found to promote hair growth in mice with hormone-induced hair loss.

Testosterone significantly affects urination differences between male and female mice.

The gene Foxn1 is important for hair growth, and understanding it may lead to new alopecia treatments.

The chapter explains that there are many genetic skin disorders affecting skin cell formation, including both common and rare types.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Women look young for their age due to larger lips, less sun damage, and genes that prevent gray hair and wrinkles.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Follicular Unit Extraction (FUE) is a less invasive hair transplant method with minimal scarring, suitable for about 60% of patients, especially those needing fewer grafts and quicker recovery.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.