August 2016 in “Journal of Investigative Dermatology” This study found that among men unresponsive to finasteride for androgenic alopecia, 56.25% showed significant hair improvement after six months of dutasteride treatment with reasonable adverse effects.
August 2026 in “Free Radical Biology and Medicine” March 2005 in “Journal of the American Academy of Dermatology” This study found that key amino acids lost from hair due to weathering can be successfully reintroduced through cosmetic treatments, improving hair strength and aesthetics.
166 citations
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April 2012 in “Journal of The American Academy of Dermatology” This study reviewed clinical data from 60 patients with frontal fibrosing alopecia and found increasing prevalence and generally poor response to treatment, with the cause remaining unclear.
This study found that the optimized AR antagonist candidate 39, in a hair-growth mouse model, achieved similar efficacy to pyrilutamide with faster onset and favorable safety, suggesting a promising approach for developing topical treatments with low systemic toxicity for androgenetic alopecia.
4 citations
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December 2020 in “Mammalian genome” This study found that pelage abnormalities in Harlequin mutant mice are linked to severe AIF deficiency and associated with altered expression of genes related to hair structure.
January 2019 in “Dermatologica Sinica” This study observed that dutasteride treatment led to improvement in acne vulgaris among two male patients with androgenetic alopecia, suggesting its potential as a treatment option for concurrent conditions.
This review discusses the use of Adiantum capillus-veneris (Maidenhair fern) extract to treat COVID-19 symptoms and reports no new clinical results, emphasizing the need for controlled trials.
June 2024 in “Skin Research and Technology” In this study, researchers observed significant differences in microbial composition between UV-induced fluorescent and non-fluorescent scalp areas in patients with androgenetic alopecia, noting a higher abundance of Cutibacterium in the fluorescent regions.
1 citations
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January 2020 in “Skin appendage disorders” Finasteride may help treat frontal fibrosing alopecia, but more research is needed.
August 2003 in “药物不良反应杂志” Combining finasteride and terazosin can cause severe allergic reactions.
January 2005 in “Psychoneuroendocrinology” In this study, finasteride altered the expression of nine proteins in the rat nucleus accumbens, suggesting new therapeutic targets and mechanisms for its effects on neuropsychiatric conditions.
January 2026 in “Stem Cell Research & Therapy” This study found that targeting the AR/miR-128-3p/IGF-1 pathway with ASLNC168501 shows potential for treating androgenetic alopecia by restoring hair follicle stem cell function and promoting hair regeneration.
July 2026 in “Journal of the American Academy of Dermatology”
January 2025 in “Clinical and Translational Medicine” This research found that exosome-derived long non-coding RNA AC010789.1, modified by FTO and hnRNPA2B1, enhanced human hair follicle stem cell proliferation against androgenic alopecia through the activation of S100A8/Wnt/β-catenin signaling pathways.
1 citations
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July 2024 in “Journal of the European Academy of Dermatology and Venereology” This review concludes that oral dutasteride has the highest evidence level for stabilizing frontal fibrosing alopecia and should be used as a first-line treatment until more randomized controlled trials are conducted.
September 2023 in “Cureus” This study reviewed early research on topical finasteride for androgenetic alopecia, finding it appears safe and promising, though further investigation is needed to determine optimal dosing, frequency, and potential applications for other types of alopecia.
44 citations
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January 2023 in “New Phytologist” This study found that low temperature triggers root hair elongation in Arabidopsis thaliana through a FERONIA-ROP2-TORC signaling pathway, also activated by nitrogen deficiency.
July 2025 in “Journal of Investigative Dermatology” DACC-based dressings are more effective than silver-based ones for treating chronic wounds with antimicrobial resistance.
17 citations
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May 2013 in “Journal of Investigative Dermatology” Mutations in β1 integrins cause embryonic death but have milder effects on skin.
172 citations
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March 2019 in “The EMBO Journal” This study found that in Arabidopsis thaliana, the interaction between extracellular leucine-rich repeat extensins and the receptor-like kinase FERONIA helps control vacuolar expansion, crucial for cellular elongation.
7 citations
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October 1985 in “Genetics Research” This study found that in chimaeric mice models, the pigment distribution and pattern were influenced by the sash genotype, demonstrating the melanocyte-autonomous nature of the beige and leaden loci.
August 2018 in “Journal of the American Academy of Dermatology” 17 citations
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July 2022 in “BMC Genomics” This study found that overexpression of the FA2H gene in cashmere goats' hair follicle cells may enhance hair proliferation and regulate genes affecting cashmere fineness.
February 2021 in “Reactions Weekly” Finasteride and dutasteride may cause macular abnormalities.
6 citations
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April 2021 in “Scientific Reports” This study found that Phytochrome A is crucial for regulating central metabolism and the transition to mature seedling proteomes in tomato seedlings grown under far-red light.
January 2005 in “FJ. Fragrance journal” February 2020 in “Zagazig University Medical Journal” In this study, 40 alopecia areata patients applied a combination of adapalene gel and mometasone furoate cream for 6 months, leading to 35% achieving full hair regrowth, though 85% experienced mild side effects like irritation.
July 2025 in “Journal of Investigative Dermatology”