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Genetic variations affecting skin structure play a key role in severe acne.

Thymol-loaded nanoparticles are a promising, natural treatment for acne that avoids antibiotics and preserves healthy skin bacteria.

Hormonal therapy is a good option for women with severe acne, especially when there's a chance of hormone imbalance.

Women with irregular periods should be checked for PCOS and treated early to prevent complications, with birth control pills helping to manage symptoms.

Homoeopaths and traditional healers in KwaZulu-Natal have different understandings and ways of treating acne.

BRL 7660, once studied for male contraception, showed promise as an acne treatment but was not developed further due to competing drugs.

ADT-G may be a useful indicator of increased androgen levels in women with acne and can be lowered with certain birth control pills.

Magnesium supplements improved quality of life for women with polycystic ovary syndrome, but didn't help with acne, hair loss, or abnormal bleeding.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Free fatty acids in sebum boost skin's defense against acne by increasing antimicrobial peptides.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.

ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.

Blocked hair follicles cause acne, and studying tiny early acne spots helps understand its severity.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Increased DHT formation in skin can cause hair loss, acne, and excessive hair growth, and antiandrogens might treat these conditions.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Hirsutism is a strong sign of high male hormones and metabolic problems in women with PCOS, but acne and hair loss are not.

Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.

The new micelle formulation delivers acne treatment more effectively and safely than current gels.

Oral contraceptives help treat hyperandrogenic disorders, improving symptoms like excessive hair and acne.