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Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

Isotretinoin is safe and effective for acne, with common side effects like dry lips; serious side effects are rare.

Acne and hidradenitis suppurativa have different causes and risk factors, but both are driven by inflammation and may benefit from treatments targeting interleukin-1.

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Cyproterone acetate was effective in treating acne, hirsutism, and alopecia with few side effects.

Isotretinoin effectively reduces acne but causes dry skin, higher skin pH, more redness, and hair loss.

The document concludes that advanced methods show the presence of P. acnes in acne lesions but do not prove it causes acne.

New ways to treat acne are being discovered.

Spironolactone is better than placebo for reducing excessive hair growth in women, but its effectiveness for acne is unclear due to small study sizes.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

Men with testicular cancer were less likely to experience baldness and severe acne.

Acne is common in women, often hormone-related, negatively affects quality of life, and requires various treatments.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

Photodynamic Therapy is an effective treatment for mild to severe acne.

Hormone therapies like birth control pills and spironolactone are safe and effective for treating women's adult acne.

Testosterone treatment in transgender teens can worsen acne, requiring careful treatment due to mental health and medication side effects.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Acne severity in women may not be linked to increased male hormone indicators like excess body hair, menstrual irregularities, or hair loss.

Acne is a temporary skin imbalance during puberty that often resolves on its own.

Hormonal antiandrogen therapy for acne is underused and can reduce the need for antibiotics.

Spironolactone is effective and safe for treating acne with minimal side effects.

Acne severity in women with PCOS is linked to younger age, lower body weight, and more body hair, but not to hormone levels.

Acne is an important sign of androgen excess disorders in women.

Women with mild acne are more likely to have polycystic ovary syndrome (PCOS) than those without acne.

Newborn acne may be linked to family history of high male hormone levels.

Acne lesions start with changes in hair follicles and increase in inflammation, suggesting a cycle that could affect treatment strategies.

Acne inversa is an epithelial-driven disease where inflammation is caused by cyst rupture, and treatments should focus on preventing tendril growth for better results.

Low-dose isotretinoin combined with pulsed azithromycin cleared acne in most patients, with mild side effects.

The document talks about hard-to-treat and rare acne types, their connection with other health issues, the importance of correct diagnosis, and the challenges in managing them.