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Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.

Equisetum debile extract, especially the ethyl acetate type, may be a promising natural ingredient for anti-hair loss products.

The study concluded that immune cells attacking hair follicles cause hair loss in alopecia, with genetics and environment also playing a role, and highlighted the potential of certain treatments.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.

The document concludes that understanding hair biology is key to treating hair disorders, with gene therapy showing potential as a future treatment.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

Some wound-healing cells can turn into fat cells around new hair growth in mice.

Hair and wool have complex microscopic structures with microfibrils and varying cystine content.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

Tooth papilla cells can help regenerate hair follicles and grow hair.

Minoxidil boosts hair growth by triggering growth factor release from specific stem cells.

Distinct β-catenin patterns are linked to cell growth, not cell death, in lung cancer.

Micrografts improve hair density and thickness without side effects.

iNKT cells can help prevent and treat alopecia areata by promoting hair regrowth.

Ecklonia cava polyphenols help increase human hair growth and reduce hair loss.

Fat stem cell particles help regrow hair.

Ranitidine and finasteride lower TMAO levels, reducing heart and kidney damage by changing gut bacteria.

Interferon gamma alone can't cause alopecia areata in C3H/HeJ mice.

Mediterranean diet with fresh herbs and vegetables lowers male hair loss risk.

mTORC1 signaling needed for quick hair follicle recovery after radiation damage.

Finasteride reduces melanin production, possibly treating hyperpigmentation and melanoma, but needs more safety research.

The review says that stem cells are beneficial for making skin replacements.

Sophora flavescens extract helps hair growth and treats hair loss.

Finasteride changes antioxidant enzyme expression, possibly affecting sperm protection in rats.

Cholesterol-modified siRNAs targeting certain genes increased hair growth in mice.

Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.