4 citations
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May 2014 in “Biochemical Society Transactions” This review discusses environmental reprogramming and the plasticity of epithelial cells, emphasizing their potential for new cell therapy approaches; it reports no new experimental results.
1 citations
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January 2014 in “PubMed” The researchers found that specialists often lack essential skills for identifying and diagnosing dermatologic conditions, underscoring the need for dermatologic consultations to improve patient care.
March 2026 in “Journal of Investigative Dermatology” This study found that GPT-4o demonstrated high concordance with in-person and image-based provider assessments in generating SALT scores for alopecia areata, suggesting its potential as an adjunct tool in clinical practice for automating these assessments.
September 2024 in “Journal of the American Academy of Dermatology” ChatGPT-4 can help with allergic contact dermatitis but shouldn't replace expert doctors.
April 2018 in “Journal of Investigative Dermatology” In this study, embryonic skin fibroblasts from day E17.5 and postnatal day P5, but not E14.5, effectively supported hair follicle formation, indicating distinct developmental states and differentiation capacities.
January 2011 in “The Chinese Journal of Dermatovenereology” In this study, DPC-hTERT cells were shown to induce hair follicle-like structures expressing specific keratin when co-injected with epithelial cells into nude mice.
September 2008 in “Acta Ophthalmologica” This study found that murine vibrissa hair follicle stem cells can differentiate into corneal epithelial-like cells in vitro when cultured with limbus-specific microenvironmental factors.
January 2006 in “Chinese Journal of Medical Aesthetics and Cosmetology” This study found that microencapsulated human hair dermal papilla cells successfully induced hair follicle regeneration on the dorsal skin of nude mice, unlike control groups with free cells or empty microcapsules.
72 citations
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December 1996 in “Journal of Investigative Dermatology” This study observed that human hair follicles were able to regenerate fiber-forming structures after the bulb was amputated and transplanted onto athymic mice, suggesting a general regenerative capacity.
26 citations
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February 2012 in “Journal of Investigative Dermatology” This study found that dermal papilla cells from human hair follicles can be reprogrammed into induced pluripotent stem cells, but their efficiency is similar to that of fibroblasts, unlike in mice.
10 citations
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February 1993 in “International Journal of Cosmetic Science” This study found that clove, olive, and turpentine oils completely prevented hair penetration by the fungi Microsporum gypseum and Trichophyton vanbreuseghemii.
8 citations
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May 2024 in “Diagnostics” This survey investigated how well an AI chatbot could generate dermoscopic language reports for dermatologists and found that participants were equally satisfied with its responses across scenarios, despite lower performance in diagnosing SCC and inflammatory dermatoses.
7 citations
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April 2024 in “Skin Research and Technology” This study found that ChatGPT provided fairly accurate answers to common psoriasis-related questions, as rated by medical experts, although it doesn't fully replace professional medical judgment or diagnosis.
3 citations
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August 2024 in “Cureus” This study found that DALL-E 2 performed poorly in generating accurate images of most pediatric dermatological conditions, highlighting the need for more domain-specific and inclusive training data.
3 citations
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June 2024 in “iScience” In this theoretical study, axolotl spinal cord regeneration was modeled using a reaction-diffusion process, suggesting that the control of regenerative response relies on cell sensitivity to the signal and its diffusion characteristics, laying groundwork for identifying the signaling mechanism.
August 2024 in “Clinical and Experimental Dermatology” This study found that while DALL-E 2 can create realistic hair images from text prompts, its accuracy in depicting specific hair disorders, like alopecia areata, often falls short, highlighting the need for AI developers to work with medical experts to improve dermatological applications.
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” In this theoretical study, the authors developed a computational model to explore whether a reaction-diffusion process could explain the signal inducing axolotl spinal cord regeneration, proposing that regeneration control depends on cell sensitivity to the signal and its diffusion characteristics.
22 citations
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June 2002 in “Journal of Medicinal Chemistry” This study found that several synthesized compounds were potent inhibitors of human steroid 5alpha-reductase type 2 and reduced prostate weights in treated rats, with compound 15 showing promise for potency in humans.
15 citations
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February 2021 in “Scientific Reports” This study identified a specific subpopulation of hair follicle stem cells in mice and humans that are essential for long-term hair regeneration, highlighting the potential for regenerative therapy.
9 citations
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July 2024 in “Toxins” This opinion article reviews various pathways through which onabotulinumtoxinA might work in medical treatments, highlighting applications beyond muscle paralysis, including pain inhibition and potential effects on hair loss and cancer cell apoptosis.
6 citations
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January 2016 in “Dermatology Review” This review discusses the role of various stem cell niches in the skin and their potential application in treating skin diseases, but reports no new clinical results.
4 citations
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October 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that the MD-3 antibody significantly improved the survival of hair follicle allografts in nonhuman primates by reducing T-cell infiltration.
3 citations
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October 2024 in “International Journal of Molecular Sciences” This review highlights the regenerative abilities of *Xenopus laevis*, focusing on how tadpoles regrow complex tail structures and the cellular and molecular mechanisms behind this. It underscores *X. laevis* as a valuable model for understanding regeneration, with insights potentially advancing regenerative medicine.
This study found that hypoxic preconditioning of nanofat from donor mice reduced its vascularization capacity in vivo, suggesting that this approach cannot currently enhance nanofat's regenerative potential.
January 2025 in “Advances in Dermatology and Allergology” This literature review conducted a comprehensive analysis of existing studies on micro-needling mesotherapy in dermatology and aims to offer a practical guide for its clinical application, though it provides no new experimental findings.
December 2023 in “Forensic science international. Genetics” This study found that the RapidHIT™ ID system can successfully obtain DNA profiles from single hair roots, particularly those with high nuclei counts.
August 2023 in “Journal of Investigative Dermatology” Skin organoids can regenerate hair by forming specific cell units with certain signals.
July 2023 in “Journal of the Mexican chemical society” This study found that Hibiscus rosa-sinensis dried leaves extract displayed the strongest pancreatic lipase inhibitory activity among 37 tested plant extracts, showing potential as an anti-obesity agent with effects comparable to the pharmaceutical drug orlistat in reducing plasma triacylglycerol levels in rats.
May 2023 in “CRC Press eBooks” This research reports that multilamellar phospholipid liposomes showed the highest follicular penetration of a water-soluble dye in vitro compared to other cosmetic vehicles, suggesting potential benefits for enhancing hair conditioning and treating hair loss.
April 2018 in “Journal of Investigative Dermatology” African spiny mice can regenerate skin and hair after wounds due to specific tissue mechanics.