Melatonin Preparations in Dermatological Practice
December 2015
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Studysummary This study suggests that incorporating exogenous melatonin in the treatment of certain skin disorders, like psoriasis and eczema, can improve treatment efficiency, normalize immune parameters, and reduce disease relapses. Our plain-language summary of this paper — not a Tressless recommendation.
The document reviewed literature on the use of exogenous melatonin in treating dermatological conditions such as psoriasis, atopic dermatitis, eczema, and androgenetic alopecia. It highlighted that melatonin, when used as part of combined therapy, could help normalize immunological parameters, increase treatment effectiveness, extend remission periods, and prevent relapses. Melatonin's role in regulating the body's circadian rhythms, its antioxidant properties, and its ability to modulate the immune system were discussed. The document also mentioned that disruptions in melatonin synthesis could lead to a desynchronization of biological rhythms, emphasizing that melatonin production is subject to a daily cycle. Studies cited in the document indicated that including melatonin in treatment plans for the mentioned skin conditions showed improvements in both immunological markers and clinical outcomes.