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Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

New treatments for male hypogonadism are effective and should be personalized.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Dutasteride is more effective than finasteride for hair loss treatment.

Dutasteride effectively treats benign prostatic hyperplasia and may reduce prostate cancer risk.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Plant extracts may help treat hormone-related hair loss.

Dutasteride works better than finasteride for hair loss, with both being safe to use.

Some herbs show promise as antiandrogenic agents.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

An apple-based supplement was found to stimulate hair protein production, which may help with hair growth.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

Scientists created cell lines from balding patients and found that cells from the front of the scalp are more affected by hormones that cause hair loss than those from the back.

Topical finasteride helps regrow hair and reduce balding without side effects.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Androgenetic alopecia is mainly caused by genetic factors and increased androgen activity, leading to hair follicle miniaturization.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.

Low-Level Laser Therapy and other light treatments for hair growth lack strong evidence and need more research.

Finasteride improves hair growth in men with androgenetic alopecia.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Some Thai plants, especially Carthamus tinctorius, could help prevent hair loss and promote hair growth without adverse effects.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.