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The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

The composition with carnitine, thioctic acid, and saw palmetto extract may effectively reduce inflammation in hair follicle cells.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Ginseng, especially red ginseng, may help regrow hair and block a hair loss-related enzyme.

Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.

Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.

Plant-based treatments can effectively and safely treat hair loss.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Finasteride blocks progesterone's effect on absence seizures in rats.

Male pattern baldness involves hormone-related hair thinning, shorter hair, and inflammation.

Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.

Finasteride reduces hair growth in women with hirsutism and works better with electrolysis.

Male tissue has more cell death than female tissue after ischemia, and some neurosteroids only protect female cells.

Finasteride microspheres help reduce hair loss for up to eight weeks with fewer side effects.

Hesperidin protects rat testicles from finasteride damage and improves sperm health.

The mouse model suggests male pattern baldness may be due to an enzyme increasing DHT and higher androgen receptor levels in hair follicles.

Some supplements may help with hair loss, but there's not enough strong evidence to recommend them without doctor advice.

New factors in female hair loss include genetics, hormones, stress, and inflammation; future treatments should also focus on these areas and consider the patient's emotional well-being.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.

Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.

The nutritional supplement improved hair quality and reduced hair loss.

Safflower extract in nanostructured carriers was more effective than minoxidil for hair growth without irritating skin.

Citrullus colocynthis fruit extract and its compound may help treat enlarged prostate.

The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.

Finasteride reduces new brain cells in male mice, possibly causing depression.