27 citations,
January 2017 in “Neuropsychopharmacology” The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.
27 citations,
May 2015 in “Neuropharmacology” Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.
27 citations,
February 2014 in “Planta Medica” Scutellaria baicalensis extract and baicalin may help prevent hair loss.
26 citations,
September 2018 in “Neurobiology of Disease” Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.
26 citations,
March 2015 in “Phytotherapy Research” Forsythiaside-A, a natural substance, can protect against hair loss and is more effective than current treatments, potentially making it a good option for hair loss treatment.
25 citations,
December 2017 in “The Journal of Clinical Endocrinology & Metabolism” Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.
25 citations,
November 2015 in “Journal of Ethnopharmacology” Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.
24 citations,
January 2020 in “International Journal of Molecular Sciences” Some plants with flavonoids may help treat hair loss and promote hair growth.
24 citations,
October 2016 in “Oncotarget” Finasteride has a higher risk of reproductive side effects than minoxidil.
24 citations,
January 2014 in “The American Journal of Chinese Medicine” The leaves of Platycladus orientalis have potential health benefits but require more research for safety and understanding how they work.
24 citations,
March 2001 in “Journal of Endocrinology/Journal of endocrinology” Red deer only have androgen receptors in neck hair cells for mane growth during breeding season.
23 citations,
April 2021 in “Journal of Clinical Medicine” Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.
23 citations,
January 2020 in “Frontiers in Pharmacology” Dihydrotestosterone affects hair growth by changing the Wnt/β-catenin pathway, with low levels helping and high levels hindering growth.
23 citations,
May 2019 in “Expert Opinion on Therapeutic Patents” New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.
23 citations,
December 2004 in “Differentiation” Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.
23 citations,
January 1998 in “Urological research” Castration and finasteride lower urinary oxalate in male rats, potentially treating urolithiasis.
23 citations,
January 1994 in “Skin Pharmacology and Physiology” Hair loss in men and women is linked to high stress hormone levels and other hormonal imbalances, suggesting treatments should be customized to each person's hormones.
23 citations,
December 1995 in “Archives of Dermatology” Combination therapy improves hair growth in advanced hair loss.
22 citations,
October 2018 in “Aesthetic Plastic Surgery” Understanding hair follicle biology and stem cell control could lead to new hair loss treatments.
22 citations,
November 2011 in “Journal of Analytical Toxicology” Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.
22 citations,
February 2002 in “Planta Medica” Compounds from Angelica koreana roots, especially osthenol, could be effective for treating conditions like prostate disease and hair loss.
22 citations,
January 2001 in “Chemical & Pharmaceutical Bulletin” Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.
21 citations,
November 2022 in “Frontiers in immunology” Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
Oral minoxidil effectively treats hair loss, with women needing lower doses (0.25 to 2.5 mg daily) and men needing higher doses (1.25 to 5 mg daily).
21 citations,
January 2021 in “Therapeutic Advances in Endocrinology and Metabolism” Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.
21 citations,
March 2019 in “Journal of The American Academy of Dermatology” The review highlights the need for more research on transgender dermatology, the role of dermatologists in gender affirmation, and the effects of hormone therapy on skin and hair.
21 citations,
July 2018 in “The Journal of Sexual Medicine” The 2018 update to the ED care model added a new severity score and stressed a detailed evaluation of both physical and psychological aspects.
21 citations,
April 2012 in “European Journal of Pharmaceutics and Biopharmaceutics” The gel with special fat-loaded particles from rice bran could be an effective skin treatment for hair loss.
20 citations,
April 2012 in “Fertility and Sterility” Finasteride causes lasting fertility decrease in rats.
20 citations,
May 2011 in “Cancer Biology & Therapy” Finasteride may improve prostate cancer treatment outcomes.