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Different people show different symptoms for genetic diseases because of how sensitive their bodies are to small changes in important factors.

A girl with a rare genetic condition affecting hair and nails also developed a common type of hair loss, suggesting a possible genetic link.

Skin cells show flexibility in healing wounds and forming tumors, with potential for treating hair disorders and chronic ulcers.

The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.

Testosterone undecanoate safely and effectively increased penis size in male children with 5-alpha-reductase deficiency.

A boy had a rare scalp condition with thickened skin and different-colored hair.

A 36-year-old person with a female appearance but male chromosomes was diagnosed with a rare enzyme deficiency affecting sexual development.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.

5-alpha-reductase inhibitors may help stabilize or slow down hair loss in some frontal fibrosing alopecia patients, but more research is needed to confirm their effectiveness and safety.

The study found that thioglycolic acid breaks down hair bonds more consistently than l-cysteine, which is less damaging to hair.

5 alpha-reductase inhibitors like finasteride may lower prostate cancer risk and improve cancer screening.

Dutasteride is the most effective hair loss treatment after 24 weeks, but finasteride leads to the most hair growth after 48 weeks.

Male mice are more susceptible to autism-like changes from valproic acid than female mice.

Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.

The side gland of Suncus murinus is a good model for studying human sebaceous glands.

AE can have varied symptoms and genetic causes, but zinc therapy helps.

Taking 5 alpha reductase inhibitor medication slightly increases the risk of depression, especially as you get older.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

Taking 5-alpha reductase inhibitors does not increase breast cancer risk in men.

A heterozygous mutation in HTRA1 can cause severe CARASIL symptoms.

Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.

People with Hidradenitis Suppurativa have less diverse skin bacteria and different bacterial metabolism than healthy individuals.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Finasteride harms Daphnia magna's reproduction, growth, and metabolism.

Different types of resting melanocyte stem cells have unique characteristics and vary in their potential to become other cells.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Androgen treatment with dihydrotestosterone may help maintain height in patients with 5-α-reductase type 2 deficiency, especially before puberty.

Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.