12 citations,
April 2018 in “Physiology & Behavior” Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.
6 citations,
February 2019 in “Scientific reports” A brain-produced steroid causes increased scratching in mice with a skin condition similar to eczema.
110 citations,
August 2015 in “Neuropsychopharmacology” High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.
50 citations,
April 2010 in “Biology direct” Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.
March 2024 in “Nutrients” Gynostemma pentaphyllum and its component damulin B could help hair grow by activating certain cell pathways.
15 citations,
July 2015 in “Journal of Essential Oil Bearing Plants” Thuja orientalis and Thuja occidentalis essential oils have medicinal properties useful for developing treatments with antimicrobial and bioactive effects.
11 citations,
February 2018 in “Archives of Pharmacal Research” Finasteride reduces melanin production, possibly treating hyperpigmentation and melanoma, but needs more safety research.
6 citations,
March 2019 in “International Journal of Molecular Medicine” Finasteride microspheres help reduce hair loss for up to eight weeks with fewer side effects.
January 2019 in “Oncogen” Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.
27 citations,
April 2017 in “British Journal of Dermatology” Hair loss involves immune responses, inflammation, and disrupted signaling pathways.
3 citations,
January 2017 in “Revista chilena de nutrición” Certain natural compounds called terpenes may help prevent prostate cancer.
Early NAS level changes affect alcohol consumption vulnerability.
5 citations,
September 2021 in “Frontiers in Cell and Developmental Biology” Dihydrotestosterone treatment on 2D and 3D-cultured skin cells slows down hair growth by affecting certain genes and could be a potential target for hair loss treatment.
2 citations,
August 2019 in “Journal of skin and stem cell” The study concludes that regulating apoptosis could lead to new treatments for various skin and hair conditions.
32 citations,
February 2014 in “Psychopharmacology” Dutasteride makes alcohol less sedating and may lead to less drinking in men.
403 citations,
November 2005 in “Journal of Endocrinology” Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.
1 citations,
September 2013 in “Elsevier eBooks” Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.
74 citations,
January 2013 in “Expert Opinion on Biological Therapy” The conclusion is that hair growth can be improved by activating hair cycles, changing the surrounding environment, healing wounds to create new hair follicles, and using stem cell technology.
1 citations,
February 2004 in “Medical Hypotheses” Certain cultural hair practices might cause baldness by affecting natural hair oils and stem cell delivery to hair follicles.
January 2018 in “Elsevier eBooks” The document explains how male reproductive hormones work and affect the body.
7 citations,
August 2022 in “Journal of Nanobiotechnology” Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.
157 citations,
May 2021 in “Endocrine Reviews” Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.
22 citations,
October 2019 in “Cerebral cortex” Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.
165 citations,
February 2014 in “Phytotherapy Research” Myrtle has various health benefits and potential for medicine development.
April 2024 in “International journal of medical science and clinical research studies” Effective acne management in PCOS includes hormone therapy, metformin, isotretinoin, weight loss, diet, exercise, and personalized treatment plans.
83 citations,
January 2015 in “World Journal of Stem Cells” Hair follicle regeneration needs special conditions and young cells.
13 citations,
August 2018 in “Journal of Molecular and Cellular Cardiology” Finasteride improves heart function and repairs damage after heart attack in mice.
47 citations,
December 2019 in “Biomaterials” Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.
23 citations,
January 2021 in “Biomedicine & Pharmacotherapy” DHT stops hair regrowth in mice, similar to human hair loss.
38 citations,
June 2018 in “Archives of Toxicology” Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.