Search
for
Sort by
Research
900-930 / 1000+ results![Emerging and Traditional 5-Alpha Reductase Inhibitors and Androgen Receptor Antagonists for Male Androgenetic Alopecia](/images/research/53ebb671-0745-4145-b7ea-26aab3b71b1e/small/26969.jpg)
research Emerging and Traditional 5-Alpha Reductase Inhibitors and Androgen Receptor Antagonists for Male Androgenetic Alopecia
![Inhibitory Effects of Pueraria Mirifica Aqueous Extracts on 5α-Reductase and Prostate Histomorphometry in Testosterone-Induced Benign Prostatic Hyperplasia Sprague Dawley Rats](/images/research/daaac45d-0113-45ff-ae4b-8c94346f104f/small/36101.jpg)
research Inhibitory Effects of Pueraria Mirifica Aqueous Extracts on 5α-Reductase and Prostate Histomorphometry in Testosterone-Induced Benign Prostatic Hyperplasia Sprague Dawley Rats
Pueraria mirifica extract may help treat benign prostatic hyperplasia.
research Vibrational Spectroscopic Investigation and Molecular Structure of a 5α-Reductase Inhibitor: Finasteride
Finasteride's molecular properties and active sites were identified using computational methods.
![Association of Treatment with 5α-Reductase Inhibitors with Time to Diagnosis and Mortality in Prostate Cancer](/images/research/99073a6e-ddec-46b2-a044-6850be04ef44/small/17598.jpg)
research Association of Treatment with 5α-Reductase Inhibitors with Time to Diagnosis and Mortality in Prostate Cancer
Treatment with 5α-reductase inhibitors is linked to a delay in prostate cancer diagnosis and may affect survival rates.
research Development of Microemulsions Containing Carthamus Tinctorius Extract for 5α-Reductase Inhibition
A microemulsion with Carthamus tinctorius extract effectively inhibits 5α-reductase and improves skin and hair follicle delivery.
research Screening of Steroid 5-Reductase Inhibitory Activity and Total Phenolic Content of Thai Plants
research The Function of 5α-Reductase in Related Diseases
![Potential Synergistic Effects of Haedoksamul-Tang and Finasteride on 5α-Reductase Inhibition and Proliferation of Human Follicle Dermal Papilla Cells](/images/research/ab8926d9-4a0f-4863-9e2d-a34e39932243/small/4528.jpg)
research Potential Synergistic Effects of Haedoksamul-Tang and Finasteride on 5α-Reductase Inhibition and Proliferation of Human Follicle Dermal Papilla Cells
HST and HST/F promote hair growth and may help treat alopecia.
![Sexual, Physical, And Overall Adverse Effects In Patients Treated With 5α-Reductase Inhibitors: A Systematic Review And Meta-Analysis](/images/research/8e8e8989-51d2-492a-85df-70952c2e474c/small/17028.jpg)
research Sexual, Physical, And Overall Adverse Effects In Patients Treated With 5α-Reductase Inhibitors: A Systematic Review And Meta-Analysis
Medications for hair loss and prostate issues can significantly increase the risk of sexual side effects and other negative symptoms.
![Administration of 45% Robusta Green Coffee Bean Ethanol Extract Solution and Its Effects on Hair Growth and 5α-Reductase Type 1 Levels in Male Wistar Rats](/images/research/514209b6-ab97-4e18-b689-750ac28ef26d/small/26451.jpg)
research Administration of 45% Robusta Green Coffee Bean Ethanol Extract Solution and Its Effects on Hair Growth and 5α-Reductase Type 1 Levels in Male Wistar Rats
Green coffee bean extract didn't grow hair but reduced a hair loss-related enzyme in rats.
research Structure of Human Steroid 5α-Reductase 2 with Anti-Androgen Drug Finasteride
research In Silico Screening of Effective Inhibitor of 5α-Reductase Type 1 for Androgenic Alopecia Treatment
![What Is the Role of 5α-Reductase Inhibitors in the Treatment of Androgenetic Alopecia? An Evidence-Based Review](/images/research/b3549a57-6b38-446f-a176-d0c13857574d/small/20170.jpg)
research What Is the Role of 5α-Reductase Inhibitors in the Treatment of Androgenetic Alopecia? An Evidence-Based Review
5α-reductase inhibitors are effective for treating hair loss in androgenetic alopecia.
![5α-Reductase Inhibitor Therapy: Should Physicians Be Concerned With Persistent Diminished Libido, Erectile Dysfunction, and Depression in a Subset of Patients?](/images/research/2521ed10-f508-4f85-a6da-8c9592de4586/small/26236.jpg)
research 5α-Reductase Inhibitor Therapy: Should Physicians Be Concerned With Persistent Diminished Libido, Erectile Dysfunction, and Depression in a Subset of Patients?
Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.
![Three-Month Treatment With a Long-Acting Gonadotropin-Releasing Hormone Agonist of Patients With Benign Prostatic Hyperplasia: Effects on Tissue Androgen Concentration, 5α-Reductase Activity and Androgen Receptor Content](/images/research/04e099b1-16af-40d8-93e0-881d1b10f2c2/small/28276.jpg)
research Three-Month Treatment With a Long-Acting Gonadotropin-Releasing Hormone Agonist of Patients With Benign Prostatic Hyperplasia: Effects on Tissue Androgen Concentration, 5α-Reductase Activity and Androgen Receptor Content
A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.
![Expression of mRNA for Androgen Receptor, 5α-Reductase, and 17β-Hydroxysteroid Dehydrogenase in Human Dermal Papilla Cells](/images/research/cfa8152f-fcc1-4596-8ef6-20532a6f28d3/small/28195.jpg)
research Expression of mRNA for Androgen Receptor, 5α-Reductase, and 17β-Hydroxysteroid Dehydrogenase in Human Dermal Papilla Cells
Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.
![Dihydrotestosterone Stimulates 5α-Reductase Activity in Pubic Skin Fibroblasts](/images/research/ccfb56ab-33f2-4160-90a2-af617b0b19cb/small/28335.jpg)
research Dihydrotestosterone Stimulates 5α-Reductase Activity in Pubic Skin Fibroblasts
Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.
research Nipple Differentiation in Fetal Male Rats Treated with an Inhibitor of the Enzyme 5α-Reductase: Definition of a Selective Role for Dihydrotestosterone
Blocking a specific enzyme in male rat fetuses leads to the development of nipples and feminized genitalia.
![5α-Reductase Inhibitors, Antiviral and Anti-Tumor Activities of Some Steroidal Cyanopyridinone Derivatives](/images/research/d6ced74d-694e-41db-8e70-7c12a8d035a1/small/14683.jpg)
research 5α-Reductase Inhibitors, Antiviral and Anti-Tumor Activities of Some Steroidal Cyanopyridinone Derivatives
Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.
research 5α-Reductase Inhibitory Components as Antiandrogens From Herbal Medicine
A plant extract was found to effectively block an enzyme related to male hormone-related diseases.
![5α-Reductase Inhibition and Hair Growth Promotion of Some Thai Plants Traditionally Used for Hair Treatment](/images/research/ac6987a9-9b68-44e9-b4d8-57b15570e4b5/small/14605.jpg)
research 5α-Reductase Inhibition and Hair Growth Promotion of Some Thai Plants Traditionally Used for Hair Treatment
Some Thai plants, especially Carthamus tinctorius, could help prevent hair loss and promote hair growth without adverse effects.
![In Vitro and In Vivo Effects of 17β-N-(4-Phenylcarbamoyl) Androst-4-en-3-one Derivatives as 5α-Reductase Inhibitors on Androgen-Dependent Glands](/images/research/e7c0a3ce-09ac-4c47-9e06-f91c86a222b9/small/11559.jpg)
research In Vitro and In Vivo Effects of 17β-N-(4-Phenylcarbamoyl) Androst-4-en-3-one Derivatives as 5α-Reductase Inhibitors on Androgen-Dependent Glands
Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.
![5α-Reductase Inhibition Prevents the Luteal Phase Increase in Plasma Allopregnanolone Levels and Mitigates Symptoms in Women with Premenstrual Dysphoric Disorder](/images/research/672039ef-07ae-4ad2-8c92-db231174611f/small/28646.jpg)
research 5α-Reductase Inhibition Prevents the Luteal Phase Increase in Plasma Allopregnanolone Levels and Mitigates Symptoms in Women with Premenstrual Dysphoric Disorder
High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.
![5α-Reductase Inhibitors in Androgenetic Alopecia](/images/research/71bfb08f-3f96-4b2c-ad65-0c18a27bd69d/small/3510.jpg)
research 5α-Reductase Inhibitors in Androgenetic Alopecia
Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.
![5α-Reductase Inhibitors/Finasteride: A Safe and Effective Treatment for Benign Prostatic Hyperplasia](/images/research/0a0d5382-d687-407c-b1b2-c7c231bfa928/small/2092.jpg)
research 5α-Reductase Inhibitors/Finasteride: A Safe and Effective Treatment for Benign Prostatic Hyperplasia
Finasteride is a safe and effective long-term treatment for prostate enlargement, reducing prostate volume and related symptoms.
![5α-Reductase Inhibitors and Male Reproduction](/images/research/3d192857-8cac-4be2-815c-e6838e5e0cc9/small/13882.jpg)
research 5α-Reductase Inhibitors and Male Reproduction
5α-Reductase inhibitors can negatively affect male sexual function and, in some cases, significantly reduce sperm count, but these effects may be reversible.
![5α-Reductase Inhibitors Alter Steroid Metabolism and May Contribute to Insulin Resistance, Diabetes, Metabolic Syndrome, and Vascular Disease: A Medical Hypothesis](/images/research/b319bbc1-b6be-464d-a316-83e9a4258dde/small/18771.jpg)
research 5α-Reductase Inhibitors Alter Steroid Metabolism and May Contribute to Insulin Resistance, Diabetes, Metabolic Syndrome, and Vascular Disease: A Medical Hypothesis
Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.
![5α-Reductase Inhibitors: The Finasteride Story](/images/research/9f6ac4ba-c05c-4d6b-8c95-c36ea9366b7a/small/2995.jpg)
research 5α-Reductase Inhibitors: The Finasteride Story
Finasteride safely treats enlarged prostate and male-pattern baldness.
![5α-Reductase Inhibitors in Men Aged 50 Years or Older with Androgenetic Alopecia: A Retrospective Study](/images/research/63e787d2-da2a-428e-9882-1cfc3433d7e2/small/5064.jpg)
research 5α-Reductase Inhibitors in Men Aged 50 Years or Older with Androgenetic Alopecia: A Retrospective Study
5ARI treatment improves hair growth in older men with minimal side effects.