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Fructus Psoraleae may help treat hair loss by inhibiting 5-α reductase and affecting the Nrf2-Keap1 pathway.

Finasteride may help reduce anxiety and depression in elderly but might cause depression in young men.

Canadian lawsuits involving 5-alpha-reductase inhibitors are related to persistent erectile dysfunction side effects, with no judgments against companies yet.

The document suggests that drugs for prostate issues might cause lasting sexual, mental, and physical health problems due to blood vessel damage in the penis.

5-Alpha-Reductase inhibitors might help slow down hair loss in Frontal Fibrosing Alopecia but are not a primary treatment and need more research.

Marine sponges from Tabuhan Island can inhibit enzymes linked to Alzheimer's and hair loss.

Finasteride does not negatively affect male reproductive function.

SHH protein helps nerve regeneration in hypertensive rats.

Using 5α-reductase inhibitors for hair loss can cause lasting sexual, physical, mental, and vascular health issues in men, even after stopping the medication.

Finasteride effectively treats hair loss and prostate issues with minimal side effects.

Finasteride may help reduce opioid use.

Dutasteride and finasteride can change hair growth genes, helping treat hair loss.

Finasteride reduces blood loss and the need for blood transfusions during and after TURP surgery.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.

Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

5-alpha-reductase inhibitors may reduce COVID-19 symptoms in bald males.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Finasteride and minoxidil together promote hair growth better than either alone.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Finasteride reduces hair growth and is safe for women with excessive hair.

5-alpha reductase inhibitors are generally safe but can cause sexual side effects and require patient education on risks.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Taking 5-α reductase inhibitors for prostate enlargement or hair loss does not significantly raise the risk of erectile dysfunction.

Taking finasteride for benign prostate hyperplasia may increase the risk of osteoporosis, especially at higher doses.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Finasteride and dutasteride can cause sexual problems like impotence and low libido.