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Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Androgen treatment with dihydrotestosterone may help maintain height in patients with 5-α-reductase type 2 deficiency, especially before puberty.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

The Hairless gene is crucial for healthy skin and hair growth.

Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

The HR protein's role as a repressor is essential for controlling hair growth.

Changes in the HR gene have influenced hair growth and may lead to hair loss conditions in humans.

Bee pollen, green tea, essential oils, and various plant extracts improve skin and hair health.

New and known mutations in the hairless gene cause a hair loss condition called Atrichia with papular lesions.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

Cetaceans lost hair due to changes in the Hr and FGF5 genes.

Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.

Methyl caprate greatly increases drug absorption through the skin and is better than other enhancers.

The Li-Pa/Ca and Do/Ca chemotherapy regimens for serous ovarian cancer showed better short-term and long-term results than the Pa/Ca regimen.

5% minoxidil works better for hair growth and density, with minor irritation.

Drugs that block DHT production can effectively treat enlarged prostate and improve urinary issues with some sexual side effects.

5% and 2% minoxidil solutions effectively promote hair growth and reduce hair loss, with 5% being slightly more effective but having more side effects.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

5α-reductase inhibitors may prevent prostate cancer but could also raise the risk of more severe cancers.

New 5% minoxidil foam effectively promotes hair growth and is safe for use.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Testosterone's muscle-building effects do not require its conversion to DHT.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

5% minoxidil foam once daily works as well as 2% minoxidil solution twice daily for female hair growth and is more convenient.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.