39 citations,
October 2013 in “Plastic and Reconstructive Surgery” Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.
36 citations,
June 2014 in “International Journal of Dermatology” Dutasteride helps hair growth in those unresponsive to finasteride, but may cause more sexual dysfunction.
32 citations,
April 1999 in “Expert Opinion on Investigational Drugs” Finasteride effectively treats male hair loss, improving growth and density.
23 citations,
July 1993 in “Pharmacotherapy” Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
20 citations,
December 1995 in “Journal of Chromatography B: Biomedical Sciences and Applications” Accurate method measures finasteride levels in human plasma using gas chromatography-mass spectrometry.
11 citations,
May 2002 in “The Journal of Urology” Finasteride doesn't harm bone density in older men with BPH.
6 citations,
August 1996 in “The Journal of Clinical Endocrinology and Metabolism” MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.
3 citations,
January 2001 in “Cambridge University Press eBooks” Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.
April 2024 in “Journal of dermatology research reviews & reports” Using a laser helmet with Minoxidil works better for male hair loss than Minoxidil alone, with no extra side effects.
August 1994 in “Molecular Endocrinology” Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.
37 citations,
January 1991 in “Reproductive Toxicology” Finasteride reduces male rat fertility by causing issues with copulatory plug formation.
May 2017 in “Journal of The American Academy of Dermatology” Microneedling with PRP and minoxidil (5%) improves hair growth more than minoxidil (5%) alone.
122 citations,
July 1990 in “Teratology” Finasteride exposure in pregnancy causes genital abnormalities in male rats.
71 citations,
January 2004 in “Dermatology” Oral finasteride works better than topical minoxidil for hair growth, both are safe.
60 citations,
December 1998 in “Clinical Pharmacology & Therapeutics” Both drugs lower DHT levels, with GI198745 being more effective.
32 citations,
June 2017 in “Journal of Pharmaceutical Sciences” Chitosan-coated nanoparticles improve skin delivery of hair loss treatments with fewer side effects.
28 citations,
January 1991 in “Reproductive Toxicology” Finasteride temporarily lowers male rat fertility without affecting libido.
21 citations,
January 2017 in “Skin Pharmacology and Physiology” Caffeine-based liquid 0.2% is as effective as minoxidil 5% for treating male hair loss.
11 citations,
December 2010 in “The Journal of Urology” Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.
10 citations,
May 2010 in “Analytica Chimica Acta” New tests detect finasteride and dutasteride in urine quickly and easily.
8 citations,
January 2013 in “Medicinal chemistry” The compound 4c showed strong potential as an anticancer agent.
7 citations,
July 2018 in “Journal of Functional Biomaterials” A new anti-baldness patch effectively treats hair loss by blocking enzymes linked to the condition.
January 2016 in “Kafkas Journal of Medical Sciences” Turkish pregnant women commonly experienced skin issues like itching and acne, and doctors mainly used topical treatments due to safety concerns during pregnancy.
3 citations,
January 2015 in “Journal of drug assessment” Taking five small dutasteride capsules is the same as taking one larger capsule.
May 2009 in “The American Journal of Dermatopathology” Mast cells play a significant role in hair loss conditions like male pattern hair loss and alopecia areata.
8 citations,
March 2015 in “PubMed” 5% minoxidil foam effectively treats female hair loss.
32 citations,
July 2016 in “PubMed” 5-alpha reductase inhibitors are generally safe but can cause sexual side effects and require patient education on risks.
1 citations,
July 2016 in “PubMed” 5% minoxidil foam is effective and safe for hair regrowth in women with hair loss.
January 2023 in “The Egyptian Journal of Hospital Medicine” Topical Valproic acid and 5% Minoxidil both significantly increase hair count in Female Pattern Hair Loss, with similar side effects.
37 citations,
April 2008 in “The Cochrane library” 5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.