May 2026 in “Skin Appendage Disorders” This review explores emerging 3D bioprinting strategies for hair follicle creation, highlighting their potential to advance alopecia treatment and trichology research, but notes the need for further optimization and reduced maintenance costs before clinical use.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study suggests that 3D bioprinting may become a practical solution for tissue regeneration and complex wound care, demonstrating improved outcomes over traditional methods in various applications.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study demonstrates that 3D bioprinting is advancing toward practical use in reconstructive medicine, with promising results in personalized skin grafts, hair regeneration, and burn care, despite existing technical and ethical challenges.
December 2025 in “Journal of Neonatal Surgery” This study reviews advancements in 3D bioprinting for dermatology, highlighting the creation of next-generation dermal fillers that are more compatible and longer-lasting than traditional ones by using living cells and safe biomaterials, with potential applications in anti-aging and tissue regeneration.
June 2026 in “Virtual and Physical Prototyping” This study introduced a high-viscosity epoxy photoresist to enhance the fabrication of complex microstructures with monolithic integration and mechanical stability, enabling advancements in two-photon 3D printing for creating functional micro-mechanical devices.
March 2024 in “International Research Journal of Modernization in Engineering Technology and Science” This article explores the use of 3D printing technology to produce hair in the beauty industry, addressing safety concerns, explaining the creation process, and highlighting its benefits over traditional hair while noting its positive environmental impact.
15 citations
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March 2022 in “Acta Biomaterialia” This study demonstrated that a 3D bioprinting technique using a gelatin/alginate hydrogel scaffold can regenerate entire hair follicles in mice, offering potential advancements in hair loss treatment.
December 2024 in “African Journal of Biomedical Research” This review discusses the potential of 3D bioprinting to revolutionize cosmetic treatments through personalized skin regeneration, facial reconstruction, and anti-aging therapies, while highlighting the current challenges and promising future in the field of cosmetology.
August 2024 in “Cosmoderma” 3D-printed hair follicles could revolutionize hair loss treatments by providing unlimited hair grafts.
May 2026 in “İzmir Katip Çelebi Üniversitesi Sağlık Bilimleri Fakültesi Dergisi” In this study, researchers successfully developed a 3D printed alginate-gelatin composite hydrogel scaffold characterized by high porosity and potential applications in drug delivery and screening, particularly for neurodegenerative diseases like Alzheimer's.
1 citations
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September 2022 in “Biomaterials advances” This study used 3D bioprinting to implant epidermal stem cells, skin-derived precursors, and Matrigel into mouse wounds, successfully regenerating hair follicles and skin components within four weeks, with minimal impact on stem cell viability and stemness.
January 2025 in “Vitalitas Medis : Jurnal Kesehatan Dan Kedokteran” This study conducted a systematic review of 3D bioprinting technology in organ and tissue engineering, highlighting its medical applications and bioethical challenges, particularly regarding embryonic stem cells and Islamic ethical perspectives on organ creation.
49 citations
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August 2022 in “Materials Today Bio” This review discusses 3D bioprinting methods for urological diseases, noting its potential to create functional organs for transplantation despite challenges in replicating organ complexity and material limitations.
1 citations
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March 2024 in “Brain Imaging and Stimulation” This study reported that a 3D-printed LED photobiomodulation device is technically and financially feasible, but requires further experimental and clinical testing before being used in human healthcare.
48 citations
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December 2022 in “Biomolecules” This review discusses recent advancements in 3D bioprinting for skin regeneration and describes potential improvements for clinical applications, but it reports no new experimental results.
28 citations
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December 2016 in “Journal of Biomedical Materials Research Part A” This study found that mesenchymal progenitor cells from human hair roots seeded onto polymer scaffolds stimulated the production of mineralized proteins, enhancing bone-like structures, with optimal results at a pore size of 35 µm.
October 2024 in “Applied Sciences” In this study, tubular 3D bioprinted structures made from sodium alginate and gelatin, containing NIH/3T3 fibroblast cells, demonstrated the ability for cell growth and network formation over 6 weeks, although structural tensile strength decreased with cell growth and polymer degradation.
49 citations
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January 2023 in “Gels” This review summarizes recent advancements in three-dimensional bioprinting technology and hydrogel bioinks, highlighting their applications in tissue engineering, but reports no new experimental results.
41 citations
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August 2024 in “Drug Delivery and Translational Research” This review discusses the development and applications of microneedles, particularly through 3D printing, highlighting their potential in transdermal drug delivery but reporting no new results.
16 citations
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January 2023 in “Molecular Biomedicine” This study demonstrated that customized microneedle arrays can precisely induce targeted hair regeneration and improve hair quality in mice, potentially offering a personalized treatment approach for hair loss.
April 2017 in “Plastic and Reconstructive Surgery – Global Open” In this study, researchers developed a 3D-printed vascular model to analyze how different shear stresses influence cell behavior and promote cellular organization around neovessels, offering insights into tissue engineering for wound reconstruction.
3 citations
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June 2025 in “Wound Repair and Regeneration” This review highlights the global efforts and challenges in 3D bioprinting for developing skin substitutes, emphasizing the need for standardized protocols to enhance reproducibility and clinical applicability in wound healing and regeneration.
February 2025 in “International Journal of Bioprinting” This study constructed a 3D-printed scaffold using sodium alginate, gelatin, and alginate lyase hydrogel, which supports hair follicle regeneration in artificial skin, suggesting a promising strategy for tissue-engineered skin with functional appendages.
This study developed and tested continuous implanters for dermal papilla cell aggregates, finding that the bar-cartridge type implanter is the most effective design for continuous cell implantation in androgenetic alopecia research.
This chapter reviews bioengineered human hair follicles and discusses the pros and cons of different 3-D bioprinting methods, but reports no new experimental findings.
4 citations
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May 2025 in “Life” This review highlights advancements in 3D bioprinting for skin tissue engineering, focusing on exosome-loaded bioinks that show potential for enhancing skin regeneration and repair.
11 citations
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September 2024 in “Journal of Advanced Research” This study found that PC 3DP models are reliable preclinical tools that could potentially customize treatment strategies and predict patient prognoses by correlating drug sensitivity profiles with clinical outcomes, though larger patient cohort validation is needed to confirm clinical utility.
January 2026 in “International journal of high school research” This review discusses how combining single-cell RNA sequencing and 3D bioprinting is advancing skin tissue engineering by enhancing cellular-level precision and addressing challenges like vascularization, ultimately improving regenerative outcomes and therapeutic strategies.
October 2021 in “Postepy Dermatologii I Alergologii” This review discusses the future potential of 3D skin bioprinting for skin regeneration and reports no new experimental results.
2 citations
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April 2024 in “Biotechnology Progress” This study designed a micromold template for creating controlled-sized, multicellular tumor spheroids, finding that HEK-293 cells formed consistent spheroids with high circularity and viability after 7 days, influenced by cell seeding density and treatment conditions.