September 2025 in “Meditsinskiy sovet = Medical Council” This study found a significant age-dependent association between alopecia areata and atopic dermatitis, with atopic dermatitis being a notable risk factor, especially in children.
June 2026 in “Indian Journal of Postgraduate Dermatology” In this reported case, a 50-year-old man developed an acneiform rash, a common skin side effect of EGFR inhibitor therapy, after starting lapatinib for breast cancer; treatment with doxycycline and hydrocortisone cream led to significant improvement within one week.
April 2026 in “JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA” In this study, the researchers successfully developed a Spanlastic gel containing EGCG for transdermal application, significantly increasing EGCG skin permeability with optimal entrapment efficiency, zeta potential, and vesicle size.
June 2025 in “International Journal of Scientific Reports” In this case report, a 61-year-old male with a painful, inflamed swelling on his ankle was diagnosed with an epidermoid inclusion cyst following surgical excision.
September 2024 in “Brazilian Journal of Hair Health” This study found that four months of oral nutrient supplements improved hair density by 16-21% and caliber by 18-22% in men and women with pollution-related hair loss, addressing oxidative damage without using finasteride, antiandrogens, or minoxidil.
August 2024 in “Indian Journal of Animal Research” In this study, dermatophytosis in cattle around Parbhani was found to have a prevalence of 17.2%, with Clove oil treatment showing the quickest recovery in 7 days.
April 2023 in “Journal of Investigative Dermatology” In this study, researchers observed distinct aging signatures in mouse keratinocytes, with increased expression in older mice, and noted relevant pathway changes that were also evident in human skin, suggesting potential insights into intrinsic skin aging.
November 2022 in “Journal of Investigative Dermatology” This study developed a chalcone-based molecule that significantly increased tyrosinase inhibition and solubility, showing potential as a safe and effective skin depigmenting and antiaging agent, with supportive epigenetic and antioxidant properties observed in vitro.
January 2022 in “Menoufia Medical Journal /Menoufia Medical Journal” This study found that alopecia areata was associated with increased serum levels of retinol-binding protein-4 compared to controls, but no correlation with disease severity was observed.
June 2021 in “Research Square (Research Square)” This study found that despite cosmetic effects from antiepileptic drugs like hair loss and weight gain, Sudanese epilepsy patients generally prioritized medication adherence, potentially influenced by cultural perceptions.
January 2006 in “Journal of Sun Yat-sen University” This study reports that tissue-engineered skin using ES cell-derived epidermal stem cells and collagen sponge successfully healed full thickness skin defects in mice, forming epidermis and structures resembling glands and hair follicles.
1 citations
,
April 2024 in “Acta Biochimica et Biophysica Sinica” This study categorizes the human fetal vaginal epithelium into four areas with distinct transcriptomic profiles, aiding potential advancements in vaginal reconstruction and drug delivery.
67 citations
,
April 2014 in “Biochemical Journal” This study found that mice deficient in ceramide synthase 4 showed altered sebum composition and progressive hair loss due to obstructed hair canals.
11 citations
,
October 2007 in “International Journal of Dermatology” This study describes the epidemiologic, clinical, and etiologic characteristics of alopecia among patients at a dermatology service, identifying tinea and alopecia areata as the most common causes.
5 citations
,
January 2016 in “Elsevier eBooks” This study found that combining AMD-3100 with FK506 in subimmunosuppressive doses enhanced stem cell release from bone marrow, resulting in 25% faster epithelialization in excisional wounds in rats and mice.
1 citations
,
April 2018 in “Revista da Sociedade Portuguesa de Dermatologia e Venereologia” This article reviews the prevalence, causes, and associated conditions of hidradenitis suppurativa, a chronic inflammatory skin disease, but reports no new clinical findings.
1 citations
,
March 2022 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that HIF-P4H-2 function in FoxD1-lineage cells is crucial for normal hair follicle development and homeostasis in mice, implicating disrupted HIF, TGF-β, and Notch signaling pathways in associated defects.
January 2026 in “Egyptian Journal of Dermatology and Venerology” This study in Egyptian children found that scalp hair loss significantly impacts quality of life, with nearly half experiencing severe emotional and social challenges, particularly those with alopecia areata and tinea capitis.
July 2025 in “Biochimica et Biophysica Acta (BBA) - Molecular Cell Research” In this study, researchers identified the miR-22-3p/CLIC4 signaling pathway as a key regulator in hair follicle miniaturization among androgenetic alopecia models, suggesting that targeting CLIC4-mediated sonic hedgehog pathway disruption may offer new therapeutic strategies for AGA treatment.
March 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that the absence of Hif-p4h-2 in specific mouse skin cells disrupted hair follicle development, leading to hair loss due to irregular keratin formation and pathway signaling.
December 2009 in “생명과학회지” This study found that thymosin β4 is highly expressed in multiple human tissues and may play a role in organ function and angiogenesis through co-localization with VEGF.
January 1993 in “Nihon Chikusan Gakkaiho” This research found that a monoclonal antibody (MAb 17) specifically reacts with certain subunits of trichocyte keratin in rats, and discovered that trichocyte keratin expression in hair and whiskers begins at different embryonic stages.
21 citations
,
November 2017 in “Scientific Reports” This study found that prostaglandin D2 reduced proliferation in bulge resident K15+ stem cells but not in other K15+ progenitor cells, suggesting differential impacts on hair follicle stem cell niches.
4 citations
,
October 1993 in “PubMed” This study observed that while valproic acid treatment in children led to occasional mild clinical and laboratory side effects, no correlation with drug plasma levels was found.
July 2020 in “Scholars journal of applied medical sciences” This study found that vomiting was the most common side effect of sodium valproate in children under two with epilepsy.
5 citations
,
February 2019 in “BioMed Research International” This study found that 32.5% of reproductive-age women in Sichuan, China, had acne, with significant associations between acne and conditions such as PCOS and hyperandrogenism.
2 citations
,
January 2023 in “BMC plant biology” This study found that root hair length and density in rice are controlled by distinct genomic regions, with 18 regions identified but no overlap between the traits.
1 citations
,
February 2022 in “Journal of the American Academy of Dermatology” This review discusses biotin supplementation for dermatological conditions and highlights the lack of strong evidence supporting its efficacy, as well as the potential for laboratory testing interference.
January 2025 in “SKIN The Journal of Cutaneous Medicine” This study of baricitinib in adults with severe alopecia areata found that after initial success, 10.9% of participants lost treatment response by Week 152. Factors like longer disease duration and severe baseline symptoms were more common in those losing response.
13 citations
,
July 2022 in “International Journal of Environmental Research and Public Health” This study found that while male COVID-19 patients in Brazil exhibited more severe symptoms and required more intensive care than females, the difference in risk of death was relatively small.