Search

everythinglearnresearchcommunity

for

Search:↓

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

New genes and pathways are important for testosterone production and male sexual development.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Licorice extract helps hair growth and may treat hair loss.

Some women with excess hair growth have a hormone condition that can't be diagnosed by blood or urine tests alone.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Neuroactive steroids may affect the risk and treatment of alcohol use disorders.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Too much androgen can cause hair loss; finasteride may help.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

Liquorice may reduce testosterone and affect male reproductive organs, potentially helping treat conditions like prostate cancer.

Sulforaphane may help with hair growth by breaking down a hormone that causes hair loss.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

Androgens, like DHT, affect hair growth and treatments like finasteride may help.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.