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A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

Finasteride effectively treats hirsutism in women, but more research needed for long-term results.

Women with acne have lower levels of a specific hormone marker than women without acne.

Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

Finasteride is a safe, effective treatment for hirsutism with fewer side effects.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

Gene variant linked to prostate cancer, hormone levels, and hair loss.

Finasteride and flutamide both reduce hair growth, but finasteride has fewer side effects.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Dutasteride makes alcohol less sedating and may lead to less drinking in men.

Intermittent low-dose finasteride works as well as daily use for treating excessive hair growth in women.

Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.

Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.

Women with low SHBG levels and a high 3a-diol G to SHBG ratio are likely to experience female pattern baldness, possibly due to a slight excess of androgens affecting sensitive hair bulbs.

Free fatty acids may increase androgen production, potentially contributing to polycystic ovary syndrome.

Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Clinical signs of excess male hormones and actual hormone levels in the blood do not always match in women with polycystic ovary syndrome.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Bisphenol-A (BPA) increases connections between brain cells and boosts their activity, but it blocks the effects of a male hormone on brain cell plasticity.