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The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

Topical therapies show promise for hair loss and acne treatment with minimal side effects.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Treatments for Frontal Fibrosing Alopecia have not been proven effective.

FPHL causes hair loss in women due to genetics and hormones; minoxidil and anti-androgens are treatments, and early intervention is advised.

FAI values above 6.4 may suggest high androgen levels and increased metabolic risks in Chinese women of reproductive age.

The document concludes that proper diagnosis and tailored long-term treatment can effectively manage androgenic disorders in women, improving patient care outcomes.

Phyto-vesicles of β-sitosterol may effectively treat hair loss.

Combination therapies for androgenetic alopecia work best but can have significant side effects and costs.

Acne is strongly linked to high BMI, hair loss, menstrual issues, family history, and eating too many sweets and fatty foods, but not to excessive hair growth.

Sebocytes play a key role in controlling androgen levels in human skin.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

Birth control pills and cyproterone acetate can help treat acne in women, especially when linked to hormonal issues.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Cyproterone acetate effectively reduced hair growth in hirsute patients by lowering androgen levels and altering androgen metabolism.

Finasteride effectively treats BPH, but needs more trials to understand potential.

The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Higher levels of unbound testosterone are linked to increased insulin resistance, especially in women with polycystic ovary syndrome.

Dutasteride and finasteride affect different cell types differently.

Higher androgen levels do not cause baldness in men.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

DHT in the human prostate is produced through multiple pathways, not just from testosterone.

Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.

Flutamide worked better than finasteride for reducing excessive hair growth in women, but had more side effects.

Acne can be managed with various treatments and requires psychological support due to its emotional impact.

Skin problems in PCOS, like excess hair, acne, and hair loss, may not always indicate high male hormone levels and need careful diagnosis for proper treatment.