42 citations,
October 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Mutations in the KRT85 gene cause hair and nail problems.
41 citations,
June 2013 in “PLOS ONE” Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.
40 citations,
March 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Growing hair follicles have high mitochondrial activity and ROS in specific regions, aiding hair formation.
38 citations,
April 2016 in “Experimental Dermatology” The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.
37 citations,
August 2014 in “Journal of experimental botany” A gene in Arabidopsis thaliana, AtPRPL1, affects root hair length but not cell wall composition.
34 citations,
August 2002 in “British Journal of Dermatology” ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.
33 citations,
February 2016 in “Journal of Experimental Botany” ROOT HAIR SPECIFIC 10 (RHS10) reduces the length of root hairs in Arabidopsis plants.
33 citations,
August 2013 in “British Journal of Dermatology” Lack of small, fine hair on the front hairline is a key sign of frontal fibrosing alopecia.
33 citations,
December 2004 in “Differentiation” Mouse amnion can turn into skin and hair follicles with help from certain cells and factors.
32 citations,
May 2018 in “Cell Cycle” Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.
32 citations,
December 2014 in “Journal of experimental botany” Certain proteins are essential for the growth of root hairs in barley.
30 citations,
April 2020 in “Stem Cell Research & Therapy” PI3K/Akt pathway is crucial for hair growth and regeneration.
30 citations,
April 2013 in “Journal of Investigative Dermatology” Radiation mainly affects keratinocyte stem cells, not melanocyte stem cells, causing hair to gray.
29 citations,
April 2020 in “Biomolecules” The 3D scaffold helped maintain hair cell traits and could improve hair loss treatments.
28 citations,
November 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” GMG-43AC may help reduce unwanted hair growth and treat certain hair loss conditions.
28 citations,
October 2004 in “Differentiation” A gene deletion causes the "hairless" trait in Iffa Credo rats.
27 citations,
September 2018 in “Nanomedicine: Nanotechnology, Biology and Medicine” Further research is needed to improve hair regeneration using stem cells and nanomaterials.
27 citations,
August 2018 in “Frontiers in Plant Science” High levels of auxin increase root hair growth by activating RSL2 and producing ROS, while high phosphate levels hinder growth by repressing RSL2.
27 citations,
November 2005 in “Archives of Dermatological Research” Choosing hair follicles at the same growth stage leads to more consistent hair growth experiments.
26 citations,
May 2019 in “PLOS ONE” Hair loss patients have different microbes in hair follicles, possibly affecting hair loss.
26 citations,
October 2017 in “Scientific reports” A special microbe helps plants absorb rock phosphate by growing on their root hairs.
25 citations,
May 2011 in “Annals of Plastic Surgery” Nonhead hair transplantation is effective for patients with limited head donor hair, but more research is needed.
24 citations,
November 2015 in “Scientific reports” Human hair has a new region with ordered filaments and the cuticle contains β-keratin sheets.
24 citations,
September 2001 in “Journal of Dermatological Science” Cyclosporin A helps damaged hair follicles regrow hair quickly.
23 citations,
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” NF-κB is crucial for different stages and types of hair growth in mice.
22 citations,
June 2012 in “Journal of Investigative Dermatology” Adiponectin may stimulate hair growth and could be a potential treatment for promoting hair growth.
22 citations,
February 2008 in “Journal of Dermatological Science” EPR spectroscopy showed that spontaneous hair growth results in thicker skin and less pigmented hair than depilation-induced growth.
20 citations,
June 2014 in “BMC genomics” Poplar seed hairs grow from the placenta at the ovary base, with endoreduplication playing a key role in their development, and share similar cellulose synthesis processes with cotton fibers.
20 citations,
July 2010 in “Skin Research and Technology” Aging makes hair thinner and rougher, with less clear edges.
19 citations,
April 2010 in “Journal of Dermatological Treatment” Partial hair follicle extraction can effectively double the number of hair follicles for transplants, with most surviving and growing normally after a year.