Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This case report describes a 49-year-old woman with Sweet syndrome who experienced complete resolution of skin lesions after a prednisone treatment regimen.

This study attempts to classify histomorphologic reactions to drugs to aid in diagnosing drug eruptions, which are common in hospitalized patients but lack specific diagnostic features.

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

In this study, hydroxychloroquine treatment in patients with scleromyxoedema led to complete or partial remission of skin symptoms and improved mobility, though it did not affect paraproteinaemia.

This review elaborates on the skin side effects of chemotherapy and emphasizes identifying and managing both common and life-threatening skin reactions, without presenting new clinical findings.

This study found that 5% topical minoxidil significantly increased hair regrowth and improved psychosocial perceptions of hair loss in men with androgenetic alopecia compared to 2% topical minoxidil and placebo over 48 weeks.

In this 48-week trial, 5% topical minoxidil was more effective than both 2% minoxidil and placebo in promoting hair growth in women with female pattern hair loss, with notable improvements in nonvellus hair count and hair growth assessments.

This study found that TCDD significantly reduced EGF receptor binding in various animal models, linked to toxic symptoms like weight loss and developmental delays, with receptor phosphorylation persisting several days.

This study found that 2-methoxyestradiol induces apoptosis in human prostate cancer cells by activating p53 through a pathway dependent on p38/JNK-mediated NFkappaB/AP-1 activation, with JNK-dependent Bcl-2 phosphorylation also playing a critical role.

This study reports that 2-(1-Adamantyl)-4H-thiochromen-4-on-6-O-sulfamate is the most potent steroid sulfatase inhibitor identified so far, exhibiting 170-fold higher activity than the lead compound estrone sulfamate.

This study found that a once-daily 5% minoxidil topical foam is as effective as a twice-daily 2% minoxidil topical solution for hair growth in women with androgenetic alopecia, with fewer side effects and greater styling convenience.

In this study, researchers found that TCDD exposure accelerated differentiation and altered gene expression in human epidermal cells, indicating the epidermal barrier as a target of TCDD-activated AHR.

In this study, TCDD administered to male rats down-regulated EGF receptor in liver plasma membranes and increased protein kinase activity, suggesting EGF receptor–mediated toxicological effects.

TCDD changes skin gene expression and may harm skin health.

This study demonstrated that the glycolytic inhibitor 2-deoxy-D-glucose enhances antiseizure effects by potentiating extrasynaptic tonic GABAergic inhibition through neurosteroidogenesis in hippocampal slices.

This review discusses the biological effects and mechanisms of THSG in antiaging and related disease treatments but reports no new experimental findings.

This study found that compound 2g inhibits steroid sulfatase effectively without exhibiting estrogenic activity, making it a promising candidate for breast cancer treatment.

This study reported that topical 2% minoxidil solution improved hair growth compared to placebo in men with early male-pattern baldness over 24 weeks, with no significant safety issues observed.

This study measured the solubility of minoxidil in various solvents, finding the highest solubility in methanol and lowest in water, with solubility correlating to temperature.

This study found that a 6-week taper of prednisone led to more than 25% hair regrowth in 30% to 47% of alopecia areata patients, and applying 2% topical minoxidil helped maintain this growth.

This study found that using 2-hydroxypropyl-ß-cyclodextrin (HP-ß-CD) to encapsulate minoxidil can create a stable aqueous solution, potentially replacing the need for organic solvents in topical treatments for androgenic alopecia.

This study found that chemically modifying hair with 2-iminothiorane hydrochloride improved the permanence of hair setting without damaging the hair by increasing disulfide bonds.

This study found that sudden hair loss in guinea pigs may serve as a potential biomarker for subacute exposure to mustard gas, and pre-treatment with N-acetylcysteine could prevent this hair loss.

This study suggests that minoxidil 2% lotion is a safe and effective treatment for enhancing eyebrows, showing better results than placebo after 16 weeks.

In this study, researchers created a new molecular salt from minoxidil and 2,4-dihydroxybenzoic acid, finding it superior to raw minoxidil for promoting hair growth in a mouse model, suggesting it may be a promising candidate for treating hair loss.

This study found that a single application of TCDD on the skin of hairless mice altered epidermal differentiation, changing keratin expression patterns similarly to a known tumor promoter.

This study found that the 2,940 nm erbium: YAG laser may promote hair growth in C57BL/6 mice by speeding up transitions in the hair cycle and increasing hair follicle numbers.

This study reports that A132, a hair dye ingredient, induces phototoxicity and photogenotoxicity via mitochondrial apoptosis when exposed to sunlight, suggesting potential risks of oxidative stress and hair damage.

This study found that metformin treatment improved clinical outcomes in Taiwanese women with polycystic ovary syndrome, notably in overweight and insulin-resistant patients.