research Expression and Function of Keratinocyte Growth Factor and Activin in Skin Morphogenesis and Cutaneous Wound Repair
KGF and activin are crucial for skin healing and repair.
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450-480 / 1000+ results research Thyroid Hormone Receptor β1 Is Expressed in the Human Hair Follicle
Thyroid hormone receptor β1 is found in human hair follicles and helps them survive.
research Finasteride Use in the Male Infertility Population: Effects on Semen and Hormone Parameters
Finasteride can reduce fertility in some men, but stopping it increases sperm count.
research Ichthyosis Follicularis with Alopecia and Photophobia in a Mother and Daughter
A mother and daughter had severe skin, hair, and eye issues linked to IFAP.
research Cyclical Changes in Rat Vibrissa Follicles Maintained In Vitro
Rat vibrissa follicles are useful for studying hair growth cycles, especially the transition from pro-anagen to anagen.
research Development of a Health-Related Quality of Life Questionnaire for Women with Androgenetic Alopecia
WAA-QOL measures impact of hair loss on women's well-being.
research Mu-Crystallin, Thyroid Hormone-Binding Protein, Is Expressed Abundantly in the Murine Inner Root Sheath Cells
μ-Crystallin may help hair growth by affecting thyroid hormone levels in mouse hair follicles.
research Dermatological Practice and Psychiatry
Many skin patients have mental health issues, so dermatologists should consider psychological care.
research Efficient In Vitro Transfection of Human Keratinocytes with an Adenovirus-Enhanced Receptor-Mediated System
The study investigated three nonviral transfection systems for gene transfer in human keratinocytes, with a focus on the adenovirus-enhanced receptor-mediated (AVET) system. The AVET system showed superior efficiency, achieving a transfection rate of 28.8%, compared to lower rates with SuperFect and no success with PrimeFector. The presence of adenovirus was crucial for effective gene delivery. The study also found that slowly adhering keratinocytes were transfected more effectively, suggesting stem cells were less efficiently transfected. The AVET system was able to correct the enzymatic defect in keratinocytes from lamellar ichthyosis patients, but was unsuccessful in organotypic cultures due to barriers like the cornified layer. Overall, the AVET system was a powerful tool for transient in vitro transfection of keratinocytes, with potential applications in gene therapy for skin diseases.
research Endogenous Skin Fluorescence Is a Good Marker for Objective Evaluation of Comedolysis
Fluorescence can effectively measure acne treatment progress.
research Suppression of Vitamin D Receptor and Induction of Retinoid X Receptor Alpha Expression During Squamous Differentiation of Cultured Keratinocytes
As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.
research Ten Years of Injectable Platelet-Rich Fibrin
Injectable platelet-rich fibrin has improved healing and regeneration in various medical fields and can be more effective than previous treatments.
research Androgenetic Alopecia in the Stump-Tailed Macaque: An Important Model for Investigating the Pathology and Antiandrogenic Therapy of Male-Pattern Baldness
research Medications for the Treatment of Androgenetic Alopecia
Effective treatments for hair loss exist; early intervention is important.
![Benzo[c]quinolizin-3-ones: A Novel Class of Potent and Selective Nonsteroidal Inhibitors of Human Steroid 5α-Reductase 1](/images/research/ff6e6cbe-cb9c-4d11-87ef-671d28ffd4fa/small/15506.jpg)
research Benzo[c]quinolizin-3-ones: A Novel Class of Potent and Selective Nonsteroidal Inhibitors of Human Steroid 5α-Reductase 1
Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.
research Functional Analysis of the Stratum Corneum of Scalp Skin: Studies in Patients with Alopecia Areata and Androgenetic Alopecia
Scalp skin barrier affects hair loss; personalized treatments needed.
research Role of Androgens in Female-Pattern Androgenetic Alopecia, Either Alone or Associated with Other Symptoms of Hyperandrogenism
Androgens significantly affect female hair loss, and hormonal treatments may help.
research Natural Pathogens of Laboratory Animals and Their Effects on Research
Fungal infections in lab animals can interfere with research.
research Leucoderma Associated With the Use of Topical Minoxidil: A Report of Two Cases
Minoxidil use may cause skin pigmentation loss.
research The Nutritional Biochemistry of Wool and Hair Follicles
Nutrients like vitamins, copper, zinc, and amino acids are crucial for healthy hair and wool growth.
research Management of Clinical Side Effects of Depot Medroxyprogesterone Acetate
To improve use of the contraceptive DMPA among adolescents, effectively manage side effects like menstrual changes and weight gain through counseling and guidance.
research Plica Neuropathica: Matting of Hair
A girl's severely tangled hair couldn't be fixed and had to be cut due to a rare condition called plica neuropathica.
research Book Reviews
The reviews critique three psychology books, noting skepticism about a personality inventory for teens, praising a practical guide on body image issues, and recommending a book on grief therapy.
research Androgen Receptor Antagonists Structure-Activity Relationships
Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.
research Androgen Binding Profiles of Two Distinct Nuclear Androgen Receptors in Atlantic Croaker (Micropogonias Undulatus)
Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.
research Mrp4, A New Mitogen-Regulated Protein/Proliferin Gene; Unique in This Gene Family for Its Expression in the Adult Mouse Tail and Ear
A new gene, mrp4, is found in mice and may play a unique role in hair follicle development in tails and ears.
research Kinetic Analysis of LY320236: Competitive Inhibitor of Type I and Non-Competitive Inhibitor of Type II Human Steroid 5α-Reductase
LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.
research The Effect of Minocycline on the Metabolism of Androgens by Human Oral Periosteal Fibroblasts and Its Inhibition by Finasteride
Minocycline may cause hair loss by increasing DHT levels, but finasteride can help counteract this effect.
research The Role of Androgens in Hidradenitis Suppurativa and the Potential Benefits of Antiandrogen Therapy
Antiandrogen therapy may be beneficial for women with hidradenitis suppurativa.
research Hospitalists for the NHS: The Role of Androgens and Antiandrogen Therapy in Hidradenitis Suppurativa
Antiandrogen therapy may help treat hidradenitis suppurativa.