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Metformin can start ovulation and may lower 17P response in PCOS, but six months is too short to improve hair growth or change body fat distribution.

Bendamustine, often combined with other drugs, is effective and less toxic for certain blood cancers, but less effective for young, fit patients with CLL.

Birt–Hogg–Dubé Syndrome requires genetic testing for accurate diagnosis due to its similarities with tuberous sclerosis.

A new gene, JMJD1C, may affect testosterone levels in men.

Mutations in the KRT85 gene cause hair and nail problems.

The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.

Mutations in certain receptors can cause diseases and offer new treatment options.

Gene mutations can cause problems in male genital development.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

Diazoxide, minoxidil sulphate, and cromakalim relax rat blood vessels by opening K+ channels, with some differences in their actions.

The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

Chemotherapy often causes hair loss, nail changes, and mouth issues, but these are usually manageable.

Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

Some hair loss disorders are caused by genetic mutations affecting hair growth.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Minoxidil and retinol together help hair grow.

Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.

Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

All treatments reduce hair growth; low dose flutamide most effective with fewer side effects.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.