Search

everythinglearnresearchcommunity

for

Search:↓

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Celsr1 is crucial for skin cell alignment, while Celsr2 has little effect on this process.

Researchers found a genetic link for hereditary hair loss but need more analysis to identify the exact gene.

The study found that certain genes are important for hedgehog skin appendage development and immunity, with spines possibly evolving for protection and infection resistance.

Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

A gene variant in KRT71 causes the curly fur in Selkirk Rex cats.

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

People who carry the 21-Hydroxylase Deficiency gene are not more likely to have excessive male hormone levels.

AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.

Hair gets thinner, grayer, and changes texture with age due to genetics, environment, and cellular changes, affecting the growth cycle.

The G60S Connexin43 mutation causes hair growth issues and poor hair quality in mice, similar to human ODDD patients.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.

Disrupting the FGF5 gene in rabbits leads to longer hair by extending the hair growth phase.

The PP2A-B55α protein is essential for brain and skin development in embryos.

A mutation in the KRT71 gene causes a hair disorder by disrupting hair follicle structure and texture.

Patients with the same genetic mutation for vitamin D-resistant rickets showed different symptoms but all improved with treatment except for hair loss.

OsUEV1B protein is essential for controlling phosphate levels in rice.

About 15% of adolescent girls in a region of India have Polycystic Ovarian Syndrome, which is more common in those born by cesarean, with wisdom teeth, or with central obesity.

Genes related to keratin, skin cell differentiation, and immune functions are key in hedgehog skin and spine development.

The meeting discussed medical findings, including benefits of certain treatments for cancer and heart conditions, and highlighted issues like poor adherence to preventive measures and skill gaps among interns.