232 citations,
January 2016 in “BMC Bioinformatics” The method can effectively extract biomedical information without needing expert annotation, performing better than previous models.
226 citations,
September 2001 in “Journal of The American Academy of Dermatology” Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.
205 citations,
August 2007 in “Experimental Cell Research” Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.
195 citations,
July 2005 in “American Journal of Human Genetics” Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.
125 citations,
September 2019 in “Journal of Clinical Immunology” Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.
95 citations,
November 2018 in “Australasian journal of dermatology” Alopecia areata treatment varies, with no optimal method established yet.
88 citations,
October 2002 in “Journal of Dermatology” Finasteride for hair loss may cause depression, affecting sleep and relationships.
85 citations,
August 2018 in “Psychological Medicine” Women with PCOS are more likely to suffer from depression, anxiety, and stress.
80 citations,
January 1988 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Spironolactone can cause side effects like irregular bleeding, but lower doses may reduce these effects and still improve hirsutism.
76 citations,
August 2007 in “Supportive care in cancer” Chemotherapy often causes skin, nail, and hair side effects, significantly impacting quality of life.
76 citations,
December 1997 in “Fertility and Sterility” Finasteride reduces hair growth better, but spironolactone has more side effects.
74 citations,
March 1963 in “Archives of Dermatology” Triparanol therapy can cause hair loss and skin dryness without inflammation or damage to hair follicles or skin structures.
72 citations,
July 2014 in “American journal of clinical dermatology” Some treatments, like corticosteroids and sensitizing agents, can help with alopecia areata, but more high-quality research is needed.
72 citations,
October 1998 in “Baillière's clinical endocrinology and metabolism” Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.
69 citations,
January 2015 in “Current problems in dermatology” Trichoscopy is a quick, noninvasive method to diagnose hair and scalp disorders, often reducing the need for biopsies.
68 citations,
January 2008 in “Seminars in reproductive medicine” Women with PCOS often feel stigmatized and have mood issues, which can lower their sexual satisfaction, but proper treatment and support can help.
65 citations,
July 2020 in “Science Advances” Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.
63 citations,
February 2013 in “Human cell” PEGL-DOX causes Hand-Foot Syndrome due to skin reactions from prolonged circulation and ROS generation.
62 citations,
February 2011 in “Expert review of dermatology” Scalp cooling can reduce chemotherapy-induced hair loss and should be available in all hospitals.
53 citations,
August 2019 in “Journal of The American Academy of Dermatology” Oral minoxidil and topical minoxidil 5% both effectively improve female-pattern hair loss with safe side effects.
53 citations,
June 2017 in “Skin appendage disorders” PRP treatment helps hair growth in most cases, but more research needed.
51 citations,
October 1980 in “The New England Journal of Medicine” Minoxidil lowers blood pressure effectively but may cause unwanted hair growth and other side effects.
49 citations,
May 2013 in “JAMA Dermatology” Hair loss links to higher death risk from diabetes and heart disease; not a direct cause, but a marker for risk factors.
47 citations,
November 1982 in “Journal of Cardiovascular Pharmacology” Nitrendipine and nifedipine effectively block muscle contractions, while papaverine relaxes them and minoxidil needs high amounts to work.
45 citations,
December 2009 in “Veterinary dermatology” The book is recommended for its new scientific information and balanced treatment options for hair loss in domestic animals.
43 citations,
November 1992 in “International Journal of Dermatology” Minoxidil 2% effectively treats female hair loss, promoting growth and density.
42 citations,
April 2011 in “European Journal of Dermatology” Early balding men may have insulin resistance, but lifestyle changes can help.
41 citations,
October 2011 in “Journal of Dermatology” Finasteride 1 mg effectively and safely increases hair growth in Japanese men with hair loss.
37 citations,
January 1987 in “Dermatology” Minoxidil stimulates hair growth by increasing hair thickness and prolonging growth phase.
35 citations,
August 1980 in “Circulation” Minoxidil may cause heart issues in animals and humans.