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Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

Stress can worsen skin conditions and stop hair growth by affecting the body's stress response system.

Polycystic ovaries are defined by having 12 or more small follicles in each ovary and are found in up to 33% of women, while Polycystic Ovary Syndrome (PCOS) is the most common hormone disorder in women of reproductive age, potentially increasing risk of obesity, diabetes, and heart diseases.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Men over 50 may experience hormone decline causing various symptoms, and proper management is crucial.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Mostly postmenopausal Caucasian women get Frontal Fibrosing Alopecia, which often includes eyebrow loss and has limited treatment success.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

DrugNet effectively identifies new uses for existing drugs and may save resources in drug development.

Comma hairs are a specific sign of tinea capitis when viewed with videodermatoscopy.

Tofacitinib helped regrow hair in most adolescents with alopecia areata, but more research is needed.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.

Deregulation of stem cell function is central to the development of some cancers.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

A genetic defect in vitamin D receptors causes severe rickets and hair loss in children, but some heal as they age.

Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.

Growth factors and cytokines are important for hair growth and could potentially treat hair loss, but more research is needed to overcome challenges before they can be used in treatments.

An mFG score of 5 or more indicates above-normal hair growth in Southern Chinese women.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

Polygonum multiflorum extract helps grow hair by activating certain hair growth signals in mice.

Finasteride may reduce prostate bleeding by lowering blood vessel growth factor levels and blood vessel density in certain prostate areas.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.

Galectin-1 helps in RNA processing in cell nuclei.