July 2022 in “JEADV Clinical Practice” The document concludes that different types of permanent hair loss conditions are related and early treatment is key to preventing further damage.
February 2024 in “The Journal of Dermatology” Dutasteride 0.5 mg is safe and effective for long-term use in Korean men with hair loss.
January 2024 in “Journal of the Egyptian Women's Dermatologic Society (Print)” Combining minoxidil with dutasteride and microneedling is more effective for female pattern hair loss than just dutasteride and microneedling.
May 2024 in “Journal of cosmetic dermatology” "Dutasteride 0.5 mg daily is the most effective treatment for male hair loss."
July 2024 in “Actas Dermo-Sifiliográficas” Finasteride and dutasteride do not significantly change beard thickness in men.
January 2022 in “Cosmoderma” Using oral minoxidil and dutasteride together can quickly increase hair growth and volume with minimal side effects.
71 citations,
November 2012 in “Expert Opinion on Drug Safety” 5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.
64 citations,
June 2009 in “Journal of The American Academy of Dermatology” Oral dutasteride can potentially treat frontal fibrosing alopecia in postmenopausal women, with some patients showing disease arrest and hair regrowth.
20 citations,
June 2017 in “Hormone Molecular Biology and Clinical Investigation” Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.
1 citations,
August 2022 in “Journal of Dermatological Treatment” Dutasteride is the most effective for hair loss but may cause sexual and mental side effects.
February 2024 in “Actas Dermo-Sifiliográficas” Dermatologists recommend oral dutasteride for male hair loss, low-dose oral minoxidil for female hair loss, and a multidisciplinary approach for young patients, with caution during pregnancy.
August 2016 in “Journal of Investigative Dermatology” Dutasteride improved hair density and thickness in men not helped by finasteride, with minimal side effects.
110 citations,
August 2015 in “Neuropsychopharmacology” High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.
Topical minoxidil and oral finasteride and dutasteride are the most effective treatments for male and female pattern hair loss, but study quality varies.
1 citations,
October 2021 in “Journal of The American Academy of Dermatology” The document concludes that treatments for hair loss in transgender and gender-diverse individuals include topical solutions, oral medications, laser therapy, and hair restoration procedures, with progress assessed after 6-12 months.
October 2021 in “Cosmoderma” Hair loss can be managed with treatments like minoxidil, finasteride, and others, but there are still gaps in effectiveness and off-label usage is increasing.
195 citations,
February 2007 in “The Journal of Clinical Endocrinology and Metabolism” Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.
6 citations,
December 2016 in “Journal of Dermatology” Dutasteride effectively and safely treats male hair loss for over a year.
1 citations,
July 2018 in “Elsevier eBooks” Heredity and hormones cause common hair loss, and topical minoxidil is the first recommended treatment.
1 citations,
June 2021 in “Singapore Medical Journal” Dutasteride and finasteride can help increase hair growth gene expression but need further improvement.
February 2013 in “Journal of The American Academy of Dermatology” Using hair loss drugs finasteride and dutasteride may cause sexual side effects.
4 citations,
July 2015 in “Veterinary Dermatology” Two types of 5α-reductase are in dog skin, which might make dutasteride better than finasteride for treating dog hair loss.
May 2024 in “Brazilian Journal of Hair Health” Finasteride and dutasteride may help prevent hair loss but could cause side effects like sexual dysfunction and psychological issues.
51 citations,
May 2013 in “The Journal of Steroid Biochemistry and Molecular Biology” Certain drugs that block specific enzymes can help treat prostate diseases.
29 citations,
July 2012 in “The Journal of Sexual Medicine” Rats had lasting erectile problems after stopping a certain medication.
December 2023 in “Annals of phytomedicine” Dutasteride is more effective than finasteride for hair loss treatment.
75 citations,
January 2014 in “Korean Journal of Urology” 5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.
29 citations,
July 2009 in “BJU international” Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.
4 citations,
August 2021 in “Biomedicine & Pharmacotherapy” 5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.