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    Did you mean Pro-inflammatory cytokines?
    Glossary Pro-inflammatory cytokines

    signaling molecules that trigger inflammation in the body

    Pro-inflammatory cytokines are signaling molecules released by immune cells that promote inflammation in the body. They play a crucial role in the immune response by helping to fight off infections and heal injuries, but excessive or chronic production can lead to inflammatory diseases such as rheumatoid arthritis, psoriasis, and alopecia areata. Examples include tumor necrosis factor-alpha (TNF-α), interleukin-1 (IL-1), and interleukin-6 (IL-6).

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    1. Common Skin Diseases and Metabolic Syndrome: A Proinflammatory Chemokine Perspective Metabolites · 2026
    2. Single‐cell RNA sequencing highlights the role of proinflammatory fibroblasts, vascular endothelial cells, and immune cells in the keloid immune microenvironment International Journal of Dermatology · 2024 · 6 citations
    3. Phosphatase Regulator NIPP1 Restrains Chemokine-Driven Skin Inflammation 2020 · 7 citations
    4. 713 Fisetin promotes differentiation, inhibits proliferative and inflammatory responses in cultured human cells and alleviates psoriasiform dermatitis in mice Journal of Investigative Dermatology · 2017
    5. Inflammatory perifollicular fibrosis and alopecia International Journal of Dermatology · 1998 · 10 citations
    6. Chemokine C-C Motif Ligand 7 (CCL7), a Biomarker of Atherosclerosis, Is Associated with the Severity of Alopecia Areata: A Preliminary Study Journal of Clinical Medicine · 2021 · 4 citations
    7. Deep skin fibroblast-mediated macrophage recruitment supports acute wound healing 2024 · 3 citations
    8. Geranyl Acetate Attenuates Para-phenylenediamine-induced Cytotoxicity, DNA Damage, Apoptosis, and Inflammation in HaCaT Keratinocytes Iranian journal of pharmaceutical research · 2025 · 1 citations
    9. Ex Vivo Treatment with Allogenic Mesenchymal Stem Cells of a Healthy Donor on Peripheral Blood Mononuclear Cells of Patients with Severe Alopecia Areata: Targeting Dysregulated T Cells and the Acquisition of Immunotolerance International Journal of Molecular Sciences · 2022 · 1 citations
    10. Assessment of chemokines MIP-1α and MIP-1 βin Iraqi women with polycystic ovarian syndrome Egyptian Journal of Immunology · 2023 · 1 citations
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