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    Did you mean Pro-inflammatory cytokines?
    Glossary Pro-inflammatory cytokines

    signaling molecules that trigger inflammation in the body

    Pro-inflammatory cytokines are signaling molecules released by immune cells that promote inflammation in the body. They play a crucial role in the immune response by helping to fight off infections and heal injuries, but excessive or chronic production can lead to inflammatory diseases such as rheumatoid arthritis, psoriasis, and alopecia areata. Examples include tumor necrosis factor-alpha (TNF-α), interleukin-1 (IL-1), and interleukin-6 (IL-6).

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    1. Common Skin Diseases and Metabolic Syndrome: A Proinflammatory Chemokine Perspective Metabolites · 2026
    2. Single‐cell RNA sequencing highlights the role of proinflammatory fibroblasts, vascular endothelial cells, and immune cells in the keloid immune microenvironment International Journal of Dermatology · 2024 · 6 citations
    3. Phosphatase Regulator NIPP1 Restrains Chemokine-Driven Skin Inflammation 2020 · 7 citations
    4. 713 Fisetin promotes differentiation, inhibits proliferative and inflammatory responses in cultured human cells and alleviates psoriasiform dermatitis in mice Journal of Investigative Dermatology · 2017
    5. Inflammatory perifollicular fibrosis and alopecia International Journal of Dermatology · 1998 · 10 citations
    6. Chemokine C-C Motif Ligand 7 (CCL7), a Biomarker of Atherosclerosis, Is Associated with the Severity of Alopecia Areata: A Preliminary Study Journal of Clinical Medicine · 2021 · 4 citations
    7. Deep skin fibroblast-mediated macrophage recruitment supports acute wound healing 2024 · 3 citations
    8. Geranyl Acetate Attenuates Para-phenylenediamine-induced Cytotoxicity, DNA Damage, Apoptosis, and Inflammation in HaCaT Keratinocytes Iranian journal of pharmaceutical research · 2025 · 1 citations
    9. Ex Vivo Treatment with Allogenic Mesenchymal Stem Cells of a Healthy Donor on Peripheral Blood Mononuclear Cells of Patients with Severe Alopecia Areata: Targeting Dysregulated T Cells and the Acquisition of Immunotolerance International Journal of Molecular Sciences · 2022 · 1 citations
    10. Assessment of chemokines MIP-1α and MIP-1 βin Iraqi women with polycystic ovarian syndrome Egyptian Journal of Immunology · 2023 · 1 citations
    11. FC053 Pro-inflammatory cytokine cascade in human plucked hair 1997
    12. Chikungunya virus infection in the skin: histopathology and cutaneous immunological response Frontiers in Microbiology · 2025 · 7 citations
    13. Editorial: Recruitment of leukocytes during resolution of inflammation Frontiers in Immunology · 2026
    14. ACKR2 limits skin fibrosis and hair loss through IFN‐β The FASEB Journal · 2021 · 10 citations
    15. FC056 The ideal catagen of the hair 1997
    16. The Cutaneous Inflammatory Response to Thermal Burn Injury in a Murine Model International Journal of Molecular Sciences · 2019 · 79 citations
    17. Inflammatory priming enhances mesenchymal stromal cell secretome potential as a clinical product for regenerative medicine approaches through secreted factors and EV-miRNAs: the example of joint disease Stem Cell Research & Therapy · 2020 · 118 citations
    18. eLife assessment: Decoding the complexity of delayed wound healing following Enterococcus faecalis infection 2024
    19. Regulation of immune response genes in the skin of allergic and clinically tolerant individuals exposed to p‐phenylenediamine Allergy · 2024 · 4 citations
    20. Update on Melasma—Part I: Pathogenesis Dermatology and Therapy · 2022 · 10 citations
    21. Employee engagement: el reto de trabajar juntos E-Deusto: conocimiento para ir por delante · 2007
    22. Protective effects of finasteride on the pulmonary immune response in a combined model of trauma-hemorrhage and polymicrobial sepsis in mice Cytokine · 2011 · 9 citations
    23. Keratins as an Inflammation Trigger Point in Epidermolysis Bullosa Simplex International Journal of Molecular Sciences · 2021 · 40 citations
    24. SnapshotDx Quiz: April 2022 Journal of Investigative Dermatology · 2022
    25. Iron-curcumin-carboxy PTIO coordinated nanoparticles with anti-inflammatory properties for enhanced diabetic wound healing Frontiers in Materials · 2026
    26. 708 SIG-1451: A topical anti-inflammatory new chemical entity for atopic dermatitis (AD) Journal of Investigative Dermatology · 2017
    27. Epidermal keratinocytes initiate wound healing and pro-inflammatory immune responses following percutaneous schistosome infection 2015 · 39 citations
    28. Pro-inflammatory Vδ1+T-cells infiltrates are present in and around the hair bulbs of non-lesional and lesional alopecia areata hair follicles Journal of Dermatological Science · 2020 · 23 citations
    29. Proinflammatory cytokines regulate epidermal stem cells in wound epithelialization Stem Cell Research & Therapy · 2020 · 65 citations
    30. Inhibition of Inflammatory Gene Expression in Keratinocytes Using a Composition Containing Carnitine, Thioctic Acid and Saw Palmetto Extract Evidence-based Complementary and Alternative Medicine · 2009 · 22 citations