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    Glossary Paracrine Factors

    signaling molecules affecting nearby cells within same tissue

    Paracrine factors are signaling molecules that are released by cells and affect nearby target cells within the same tissue. Unlike hormones that travel through the bloodstream to distant sites, paracrine factors act locally to regulate processes such as cell growth, differentiation, and immune responses. For example, in the context of hair growth, paracrine factors can influence the behavior of hair follicle cells, potentially impacting conditions like alopecia.

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    1. Comparative Study of Some Potential Paracrine Factors Produced by Normal and Androgenetic Alopecia Hair Follicles American journal of medical and biological research · 2015
    2. Narrow-band red LED light promotes mouse hair growth through paracrine growth factors from dermal papilla Journal of Dermatological Science · 2011 · 23 citations
    3. ‘Neurotrophology’ of the hair follicle: neurotrophins act as auto‐ and paracrine growth factors and immunomodulators Experimental dermatology · 2006
    4. Biomaterials Functionalized with MSC Secreted Extracellular Vesicles and Soluble Factors for Tissue Regeneration Advanced functional materials · 2020 · 220 citations
    5. Local Injection of Hepatocyte Growth Factor/Scatter Factor (HGF/SF) Alters Cyclic Growth of Murine Hair Follicles Journal of Investigative Dermatology · 1998 · 109 citations
    6. The chemotactic effect of a dermal papilla cell-derived factor on outer root sheath cells Journal of Dermatological Science · 2001 · 47 citations
    7. Paracrine crosstalk between human hair follicle dermal papilla cells and microvascular endothelial cells Experimental Dermatology · 2015 · 35 citations
    8. ACOS23O-002: The Use of Bone Marrow Mesenchymal Stem Cell Derived Cytokines and Growth Factors in The Management of Androgenetic Alopecia Journal of Asia Pacific Aesthetic Sciences · 2023
    9. Fibroblast growth factor and epidermal growth factor in hair development 1993 · 39 citations
    10. Protein Kinase C Epsilon Signals Ultraviolet Light-induced Cutaneous Damage and Development of Squamous Cell Carcinoma Possibly Through Induction of Specific Cytokines in a Paracrine Mechanism¶ Photochemistry and Photobiology · 2005 · 28 citations
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