research Treatment of female pattern hair loss with oral antiandrogens
This study found that 88% of women with female pattern hair loss who received oral antiandrogens saw no progression or improvement in their condition.
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5 / 1000+ resultsresearch Bicalutamide: A potential new oral antiandrogenic drug for female pattern hair loss
This article discusses the potential of oral bicalutamide as a promising treatment for female pattern hair loss and reports no new clinical results.
research The Effect of Mesenchymal Stem Cells Derived-Conditioned Media in Combination with Oral Anti-Androgenic Drugs on Male Pattern Baldness: An Animal Study.
In this study using animal models, umbilical cord stem cell conditioned media combined with oral anti-androgens improved hair regeneration in androgenetic alopecia, enhancing hair follicle cycles and reducing inflammation, suggesting potential as a promising therapy.
research Oral Contraceptives and Antiandrogens Most Effective for Hirsutism Pharmacotherapy.
This meta-analysis found that combination oral contraceptive pills effectively treat hirsutism but recommends adding an antiandrogen if response is inadequate after six months.
research 32571 Intensive dutasteride mesotherapy protocol (IDMP) with oral minoxidil as an alternative to antiandrogens in AGA. A retrospective analysis of a hair restoration center
In this study, the authors highlight the potential of intradermal microinjections of dutasteride as an adjunctive therapy for androgenetic alopecia, though they note that information on its effectiveness remains limited.
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10 / 16 results- Is pyrilutamide a safer alternative to oral antiandrogens like finasteride? Pyrilutamide (KX-826) is an unapproved, investigational topical antiandrogen whose safety data come from short-term sponsor announcements, not peer-reviewed studies. No study has compared it with finasteride, so there is no evidence that it is safer.
- Is Vitis vinifera more effective in oral supplements or topical products? Neither oral nor topical grape extract has been tested for hair loss in a human trial; topical use has only a theoretical, mouse-based rationale.
- Topical or oral? Choosing between pills and lotions according to your case. In studies, topical finasteride gave much lower blood levels of the drug than tablets but still lowered blood DHT, and whether it causes fewer side effects has not been established. There is no FDA-approved topical finasteride, and the FDA warned about compounded versions in April 2025.
- Is metformin used topically for hair loss, or only as an oral tablet? Approved metformin products are oral tablets only; there is no approved topical metformin for hair loss. Published human reports of topical use are a handful of uncontrolled, pharmacy-compounded case reports in scarring alopecia, and the most-cited clinical series actually used the oral drug.
- Is sulforaphane used in oral supplements or topical hair treatments? Sulforaphane is primarily used in oral supplements, not topical hair treatments.
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Nonsteroidal anti-androgen, originally a prostate cancer drug
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a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor
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Blood-pressure and diuretic drug with anti-androgen effects
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5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride
learn Ketoconazole
Antifungal, best known as a dandruff shampoo
learn Vitis vinifera
learn Finasteride
learn Metformin
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5 / 1000+ resultscommunity Anti-androgen use causing testicular pain?
Switching from topical finasteride to oral Dutasteride and using Fluridil caused persistent testicular discomfort. The discomfort did not subside after stopping Fluridil, raising concerns about Dutasteride's role.
community How good are anti-androgens? Are they worth seeking?
The conversation discusses hair loss treatments, including dutasteride, oral minoxidil, finasteride, and potential additions like topical finasteride, minoxidil, micro-needling, and topical anti-androgens such as RU58841. The effectiveness and worth of these treatments, including localized dutasteride mesotherapy, are considered.
community Is RU58841 or pyrilutamide a stronger topical anti-androgen?
The conversation discusses adding either RU58841 or pyrilutamide to a hair loss treatment regimen that already includes oral dutasteride and oral minoxidil. RU58841 is considered the stronger anti-androgen but may have more side effects.
community Thoughts about ORAL ketoconazole? (pills)
Oral ketoconazole is discussed as a potential hair loss treatment, but it poses significant health risks like liver damage and adrenal insufficiency. Users suggest safer alternatives like topical anti-androgens or spironolactone, emphasizing the importance of consulting a specialist.
community How to choose between topical antiandrogen (Pyrilutamide) vs topical Alfatradiol (17α-estradiol) as an add-on treatment?
The user is considering adding Pyrilutamide or Alfatradiol as a topical treatment for hair loss after oral Finasteride and Dutasteride became less effective. Other users suggest Pyrilutamide for its safety profile, while one user shares positive experiences with RU58841 for reducing scalp itch and improving hairline.
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