How to choose between topical antiandrogen (Pyrilutamide) vs topical Alfatradiol (17α-estradiol) as an add-on treatment?
    Treatment 11/5/2025

    At a glance
    In this question or advice post, the primary subjects mentioned are
    💊 Finasteride (oral) 7 years
    💊 Dutasteride (oral) almost 3 years
    💧 Ketoconazole shampoo (topical)
    • Laser cap
    💧 Pyrilutamide (topical)
    💧 Alfatradiol (topical)
    the tone is 😐 neutral with losing ground quickly results.
    The user is considering adding Pyrilutamide or Alfatradiol as a topical treatment for hair loss after oral Finasteride and Dutasteride became less effective. Other users suggest Pyrilutamide for its safety profile, while one user shares positive experiences with RU58841 for reducing scalp itch and improving hairline.
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