Search

for
Search:

Did you mean Matrix Metalloproteinase-1?

Glossary Matrix Metalloproteinase-1

enzyme that breaks down collagen in connective tissues

Matrix Metalloproteinase-1 (MMP-1), also known as interstitial collagenase, is an enzyme that breaks down collagen, a key structural protein in the skin and other connective tissues. This process is crucial for normal tissue remodeling and repair, but excessive MMP-1 activity can contribute to conditions like skin aging and certain diseases by degrading too much collagen.

Related Terms

Research

5 / 1000+ results

research A polymorphism in the matrix metalloproteinase-1 gene promoter is associated with the presence of polycystic ovary syndrome in Caucasian women

8 citations , May 2005 in “Fertility and Sterility”

In this study, women with the GG polymorphism of the MMP1 gene promoter were found to have a higher likelihood of being diagnosed with polycystic ovary syndrome.

research In-Vitro Anticancer Activity of Chemical Constituents from Etlingera alba Poulsen against Triple Negative Breast Cancer and in silico Approaches towards Matrix metalloproteinase-1 Inhibition

7 citations , May 2022 in “Indonesian Journal of Science and Technology”

This study found that compounds isolated from the Etlingera alba rhizome exhibited cytotoxic and anti-metastatic activity, with potential for development against Triple-Negative Breast Cancer.

research Expression of matrix metalloproteinases and tissue inhibitor of matrix metalloproteinases in the hair cycle

21 citations , May 2016 in “Experimental and Therapeutic Medicine”

In this study, the researchers observed that MMP-2 and MMP-9 significantly fluctuated with the hair growth cycle in mice, suggesting their important role in hair development.

Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1

research Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1

3 citations , July 2020 in “Frontiers in Cell and Developmental Biology”

This study found that the purified compound VB1 from Vitex negundo seeds may reduce UVA-induced skin aging by targeting MAPK1 and demonstrated its potential in mice.

research Oral Centella asiatica Extract Attenuates UVB-Induced Skin Photoaging via Antioxidant, Anti-Inflammatory, and Extracellular Matrix-Preserving Effects in Hairless Mice

December 2025 in “International Journal of Molecular Sciences”

In this study, orally administered Centella asiatica extract, standardized for asiaticoside content, significantly improved skin barrier function, elasticity, and reduced signs of UVB-induced photoaging in hairless mice, highlighting its potential as a nutricosmetic for skin health.

View more "matrix metalloproteinase-11" in research →

Clinics

3 / 4 results

Learn

— no results

Try a deeper search in learn →

Community Join

— no results

Try a deeper search in community →

Experts

— no results

Try a deeper search in experts →