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    Did you mean Matrix Metalloproteinase-1?
    Glossary Matrix Metalloproteinase-1

    enzyme that breaks down collagen in connective tissues

    Matrix Metalloproteinase-1 (MMP-1), also known as interstitial collagenase, is an enzyme that breaks down collagen, a key structural protein in the skin and other connective tissues. This process is crucial for normal tissue remodeling and repair, but excessive MMP-1 activity can contribute to conditions like skin aging and certain diseases by degrading too much collagen.

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    Research 30 of 1000+

    1. A polymorphism in the matrix metalloproteinase-1 gene promoter is associated with the presence of polycystic ovary syndrome in Caucasian women Fertility and Sterility · 2005 · 8 citations
    2. In-Vitro Anticancer Activity of Chemical Constituents from Etlingera alba Poulsen against Triple Negative Breast Cancer and in silico Approaches towards Matrix metalloproteinase-1 Inhibition Indonesian Journal of Science and Technology · 2022 · 7 citations
    3. Expression of matrix metalloproteinases and tissue inhibitor of matrix metalloproteinases in the hair cycle Experimental and Therapeutic Medicine · 2016 · 21 citations
    4. Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1 Frontiers in Cell and Developmental Biology · 2020 · 3 citations
    5. Oral Centella asiatica Extract Attenuates UVB-Induced Skin Photoaging via Antioxidant, Anti-Inflammatory, and Extracellular Matrix-Preserving Effects in Hairless Mice International Journal of Molecular Sciences · 2025
    6. Expression Profiling and Cellular Localization of Genes Associated with the Hair Cycle Induced by Wax Depilation 2005 · 27 citations
    7. Effects of autologous platelet‑rich plasma injections on facial skin rejuvenation Experimental and Therapeutic Medicine · 2020 · 40 citations
    8. Anti-aging effect of <i>Grateloupia elata</i> extract in skin Journal of Applied Biological Chemistry · 2025
    9. Scarless wound healing: Transitioning from fetal research to regenerative healing Wiley Interdisciplinary Reviews-Developmental Biology · 2018 · 79 citations
    10. Modulation of Photoaging-Induced Cutaneous Elastin: Evaluation of Gene and Protein Expression of Markers Related to Elastogenesis Under Different Photoexposure Conditions Dermatology and Therapy · 2021 · 14 citations
    11. Antioxidant Capacity and Protective Effect of Cow Placenta Extract on D-Galactose-Induced Skin Aging in Mice Nutrients · 2022 · 4 citations
    12. Radiofrequency Currents Modulate Inflammatory Processes in Keratinocytes International Journal of Molecular Sciences · 2024 · 3 citations
    13. Identification of immune microenvironment changes, immune-related pathways and genes in male androgenetic alopecia Medicine · 2023
    14. In Vivo Evaluation of<i>Eclipta alba</i>Extract as Anticancer and Multidrug Resistance Reversal Agent Nutrition and Cancer · 2014 · 9 citations
    15. Matrisomal components involved in regenerative wound healing in axolotl and <i>Acomys</i>: implications for biomaterial development Biomaterials Science · 2023
    16. Desmodesmus pannonicus Water Extract Inhibits Melanin Synthesis and Promotes Wound Healing Life · 2024 · 1 citations
    17. Procyanidins attenuate neuropathic pain by suppressing matrix metalloproteinase-9/2 Journal of Neuroinflammation · 2018 · 22 citations
    18. Wound Healing: A Cellular Perspective Physiological Reviews · 2018 · 1160 citations
    19. Comparison of two ASC-derived therapeutics in an in vitro OA model: secretome versus extracellular vesicles Stem Cell Research & Therapy · 2020 · 60 citations
    20. Update in minimally invasive periorbital rejuvenation with a focus on platelet‐rich plasma: A narrative review Journal of cosmetic dermatology · 2020 · 15 citations
    21. Antiaging Activity of Peptide Identified from Fermented <i>Trapa Japonica</i> Fruit Extract in Human Dermal Fibroblasts Evidence-based Complementary and Alternative Medicine · 2020 · 14 citations
    22. Facial pore refining by targeting dermal and epidermal functions: Assessment across age and gender Journal of Cosmetic Dermatology · 2024 · 6 citations
    23. <i>Col4a2-eGFP</i>mouse model reveals the molecular and functional dynamics of basement membrane remodelling in hair follicle morphogenesis bioRxiv (Cold Spring Harbor Laboratory) · 2023
    24. The effects of infrared radiation on the human skin Photodermatology, Photoimmunology and Photomedicine · 2023
    25. Self-organization process in newborn skin organoid formation inspires strategy to restore hair regeneration of adult cells Proceedings of the National Academy of Sciences of the United States of America · 2017 · 92 citations
    26. Identifying key components and therapeutic targets of the immune system in hidradenitis suppurativa with an emphasis on neutrophils 2020 · 16 citations
    27. Investigation of the molecular alterations associated with the efficacy of microneedling therapy and its potential applications in medical and dental practices Pomeranian Journal of Life Sciences · 2024 · 1 citations
    28. An in silico approach to the identification of potential proteomic and genomic diagnostic biomarkers for primary cicatricial alopecia Experimental Dermatology · 2021
    29. Effects of natural products on skin inflammation caused by abnormal hormones secreted by the adrenal gland Frontiers in Pharmacology · 2023 · 2 citations
    30. Referee report. For: Molecular mediators involved in skin healing: a narrative review [version 1; peer review: 1 approved with reservations] Faculty of 1000 Research Ltd · 2022