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Did you mean M1 Macrophages?

GlossaryM1 Macrophages

pro-inflammatory immune cells activated to fight infections

M1 macrophages, also known as classically activated macrophages, are a type of immune cell that plays a crucial role in the body's defense against infections. They are activated in response to signals like interferon-gamma (IFN-γ) and are known for their pro-inflammatory properties, which help to kill pathogens and initiate inflammation. These cells are essential for fighting off infections but can also contribute to chronic inflammation if not properly regulated.

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research Single-Cell RNA Sequencing Reveals Cellular and Transcriptional Changes Associated With M1 Macrophage Polarization in Hidradenitis Suppurativa

22 citations , August 2021 in “Frontiers in medicine”

Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.

Human Adipose Tissue-Derived Small Extracellular Vesicles Promote Soft Tissue Repair Through Modulating M1-To-M2 Polarization Of Macrophages

research Human Adipose Tissue-Derived Small Extracellular Vesicles Promote Soft Tissue Repair Through Modulating M1-To-M2 Polarization Of Macrophages

2 citations , April 2023 in “Stem Cell Research & Therapy”

Tiny fat-derived particles can help repair soft tissues by changing immune cell types.

research Macrophage Related Chronic Inflammation in Non-Healing Wounds

228 citations , June 2021 in “Frontiers in Immunology”

Macrophage issues cause chronic wound inflammation, but therapies can help.

research Macrophages Are Necessary for Skin Regeneration During Tissue Expansion

44 citations , January 2019 in “Journal of Translational Medicine”

Macrophages are essential for successful skin growth in reconstructive surgery.

Sustained Exosome-Guided Macrophage Polarization Using Hydrolytically Degradable PEG Hydrogels for Cutaneous Wound Healing: Identification of Key Proteins and miRNAs, and Sustained Release Formulation

research Sustained Exosome-Guided Macrophage Polarization Using Hydrolytically Degradable PEG Hydrogels for Cutaneous Wound Healing: Identification of Key Proteins and miRNAs, and Sustained Release Formulation

40 citations , March 2022 in “Small”

Hydrogel with M2-derived exosomes improves wound healing by slowly releasing exosomes that help reduce inflammation and promote tissue repair.

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community Just to show you the superiority of dutasteride over finasteride (it's huge)

in Research/Science 58 upvotes 1 year ago

Dutasteride is shown to be significantly more effective than finasteride for treating male androgenic alopecia. Users discuss the difficulty of obtaining dutasteride in some countries and share personal experiences with its effectiveness and side effects.

community (22 M) 1 month on Minoxidil + Topical Fin + Dermarolling – Am I on the right track? Need advice

in Progress Pictures 6 upvotes 1 week ago

A 22-year-old is using Minoxidil, topical Finasteride, and dermarolling for hair loss, seeing tiny colorless hairs after one month. Users advise patience, suggesting visible results may take 3-6 months, with significant progress over years, and recommend considering oral treatments and possibly a hair transplant in the future.

community [25 M] 1-year progress, really happy so far

in Progress Pictures 66 upvotes 11 months ago

A user shared their 1-year hair regrowth progress using 1mg oral Finasteride, 5mg oral Minoxidil, 6% Minoxidil spray, Ketoconazole shampoo, and Hawthorne thickening shampoo and conditioner. They experienced thicker body hair as a side effect but no other issues.

community 32 M 1 year anniversary on Fin

in Progress Pictures 154 upvotes 1 year ago

A 32-year-old man has been using topical minoxidil for 11 years and oral finasteride for 1 year, along with a dermaroller, and is happy with his hair regrowth progress without experiencing side effects. Commenters are impressed and some are considering starting finasteride after seeing his results.

community (20 M) 1 Year of Progress Fin and Min

in Progress Pictures 1230 upvotes 2 years ago

A 20-year-old man shared his one-year progress using finasteride and minoxidil for hair loss. He experienced no side effects, saw results within weeks, and despite occasional shedding, his hair grew back thicker and in previously bald spots.

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