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Did you mean Perifollicular Lymphocytic Infiltrate?

GlossaryPerifollicular Lymphocytic Infiltrate

presence of immune cells around hair follicles

Perifollicular Lymphocytic Infiltrate refers to the presence of immune cells, specifically lymphocytes, around hair follicles. This condition is often seen in various types of hair loss disorders, such as alopecia areata, where the immune system mistakenly attacks the hair follicles, leading to hair loss.

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research Case for Diagnosis: Pregnant Woman in the Third Trimester with Pruritic Papules and Pustules on the Trunk. Pruritic Folliculitis of Pregnancy

November 2021 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia”

The woman has a rare, harmless skin condition specific to pregnancy that causes itchy bumps and will go away after she gives birth.

Permanent Scalp Alopecia Related to Breast Cancer Chemotherapy by Sequential Fluorouracil/Epirubicin/Cyclophosphamide (FEC) and Docetaxel: A Prospective Study of 20 Patients

research Permanent Scalp Alopecia Related to Breast Cancer Chemotherapy by Sequential Fluorouracil/Epirubicin/Cyclophosphamide (FEC) and Docetaxel: A Prospective Study of 20 Patients

68 citations, May 2012 in “Annals of Oncology”

Some breast cancer chemotherapy can cause permanent hair loss.

Clinical and Histopathological Features and Potential Pathological Mechanisms of Skin Lesions in COVID-19: Review of the Literature

research Clinical and Histopathological Features and Potential Pathological Mechanisms of Skin Lesions in COVID-19: Review of the Literature

80 citations, June 2020 in “Dermatopathology”

COVID-19 can cause various skin lesions, which may result from the virus and immune response, and are not directly linked to illness severity.

research A Current Review of the Cutaneous Manifestations of Renal Disease

67 citations, September 2003 in “Journal of cutaneous pathology”

Skin problems are very common in people with end-stage kidney disease.

research Dermatologic Manifestations of COVID-19: A Comprehensive Systematic Review

27 citations, November 2020 in “International Journal of Dermatology”

COVID-19 can cause skin issues like chilblains and rashes, which may help in early detection, especially in patients without other symptoms.

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Lost density 60% all over scalp in 120 days (4months)

in Update 10 upvotes 5 months ago

A user lost 60% hair density in 4 months, started finasteride and microneedling, and has greasy, flaky, yellowish scalp. They are awaiting biopsy results, and another user suggested trying ketoconazole shampoo.

community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 43 upvotes 2 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.