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GlossaryPerifollicular Lymphocytic Infiltrate

presence of immune cells around hair follicles

Perifollicular Lymphocytic Infiltrate refers to the presence of immune cells, specifically lymphocytes, around hair follicles. This condition is often seen in various types of hair loss disorders, such as alopecia areata, where the immune system mistakenly attacks the hair follicles, leading to hair loss.

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research Case for Diagnosis: Pregnant Woman in the Third Trimester with Pruritic Papules and Pustules on the Trunk. Pruritic Folliculitis of Pregnancy

November 2021 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia”

The woman has a rare, harmless skin condition specific to pregnancy that causes itchy bumps and will go away after she gives birth.

Permanent Scalp Alopecia Related to Breast Cancer Chemotherapy by Sequential Fluorouracil/Epirubicin/Cyclophosphamide (FEC) and Docetaxel: A Prospective Study of 20 Patients

research Permanent Scalp Alopecia Related to Breast Cancer Chemotherapy by Sequential Fluorouracil/Epirubicin/Cyclophosphamide (FEC) and Docetaxel: A Prospective Study of 20 Patients

68 citations, May 2012 in “Annals of Oncology”

Some breast cancer chemotherapy can cause permanent hair loss.

research Frontal Fibrosing Alopecia: An Observational Single-Center Study of 306 Cases

June 2023 in “Life”

The study concluded that Frontal fibrosing alopecia can affect younger people, is often missed in men, and may be autoimmune-related.

research Methotrexate Injection Site Reactions: Case Report and Literature Review

1 citations, March 2022 in “JAAD case reports”

Methotrexate injection site reactions are rare but can be managed by changing injection sites and using topical treatments.

research General Dermatology: Comprehensive Overview of Dermatological Conditions

January 2017 in “Springer eBooks”

The document explains various skin conditions and their treatments.

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community Dutasteride Isn't Working? Get a Scalp Biopsy NOW

in Finasteride/Dutasteride 19 upvotes 2 weeks ago

Dutasteride may not be effective for everyone due to underlying issues, suggesting scalp biopsies for further diagnosis. Users discuss using higher doses of dutasteride, topical treatments, minoxidil, and pyrilutamide for hair loss management.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 6 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Lost density 60% all over scalp in 120 days (4months)

in Update 10 upvotes 9 months ago

A user lost 60% hair density in 4 months, started finasteride and microneedling, and has greasy, flaky, yellowish scalp. They are awaiting biopsy results, and another user suggested trying ketoconazole shampoo.

community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 43 upvotes 6 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.