A Woman With Nodules and Depressed Scars

    October 1991 in “ Archives of Dermatology ”
    B. Alibrandi, Aurora Parodi, Alfredo Rebora
    TLDR The woman has a skin condition involving nodules, scars, and hair loss.
    A 59-year-old woman exhibited cicatricial alopecia on her scalp, a painless deep nodule on her right arm, and plaques on her breasts, all of which developed over the past 20 years. The nodule and plaques were characterized by erythematous, depressed, and atrophic skin. A biopsy of the arm lesion revealed a lymphocytic perivascular infiltrate and replacement of fat lobules by hyalinized collagen. Direct immunofluorescence indicated granular deposits of IgM and C3 in the dermal vessels and around hair follicles.
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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      by nkrata in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community You will lose hair if your prostaglandins aren't in balance

      in Research/Science  54 upvotes 11 months ago
      Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.

      community Don't leave a boy hanging, try to help.

      in Chat  113 upvotes 1 year ago
      A user shared their success with oral finasteride and topical minoxidil for hair loss, recommending these treatments to others. They emphasized the importance of informing others about effective treatments rather than relying on supplements.

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