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    GlossaryKeratinocyte Differentiation (keratinocyte maturation)

    process where skin cells mature and produce protective keratin

    Keratinocyte differentiation, also known as keratinocyte maturation, is the process by which keratinocytes, the primary cells in the outer layer of the skin, develop and change as they move from the deeper layers to the surface. During this journey, they produce keratin, a protective protein, and eventually form the tough, outermost layer of the skin that acts as a barrier against environmental damage. This process is crucial for maintaining skin integrity and function.

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