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      learn GHK-Cu

      a copper peptide showing promise in both regrowth and reversing gray hair

      learn Melatonin

      hormone commonly taken for sleep aid has some topical benefits for hair

      learn Valproic acid

      an anticonvulsant repurposed for hair loss via histone inhibition

      learn Vitamin D

      vitamin you should probably be taking for general health might also help your hair a little

      learn Sulforaphane

      compound from cruciferous vegetables has some mild effects on DHT

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      community Topical finasteride now the safest possible path?

      in Finasteride/Dutasteride  84 upvotes 9 months ago
      Topical finasteride is considered a safer option for hair regrowth with fewer systemic side effects compared to oral finasteride. Some users report similar efficacy and side effects between topical and oral treatments, while others prefer topical due to reduced systemic exposure.

      community If PP405 goes systemic this would be quite catastrophic

      in Research/Science  3 upvotes 3 months ago
      Concerns about the potential systemic effects and safety of PP405 for hair loss, with discussions on its comparison to existing treatments like finasteride and minoxidil. Users express skepticism about untested research chemicals and emphasize the importance of clinical trials to ensure safety and efficacy.

      community Having androgen receptor density and sensitivity at wrong f*ing place

      in Satire  7 upvotes 6 months ago
      The conversation discusses hair loss treatments, focusing on the use of topical minoxidil, microneedling, finasteride, and dutasteride, while debating the role of testosterone and DHT in hair loss. It also touches on the potential liver health impacts of these treatments and the genetic sensitivity of hair follicles to androgens.

      community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

      in Research/Science  92 upvotes 2 years ago
      The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.