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    Did you mean Histone Deacetylases?
    Glossary Histone Deacetylases

    enzymes that remove acetyl groups from histone proteins

    Histone Deacetylases (HDACs) are enzymes that remove acetyl groups from histone proteins, leading to a more compact and less accessible form of DNA. This process can suppress gene expression by making it harder for transcription factors to access the DNA. HDACs play a crucial role in regulating gene activity and are involved in various biological processes, including cell cycle progression and differentiation.

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    1. HDAC6-dependent deacetylation of NGF dictates its ubiquitination and maintains primordial follicle dormancy Theranostics · 2024
    2. Integration of Biochemical and Mechanical Signals at the Nuclear Periphery: Impacts on Skin Development and Disease Stem cell biology and regenerative medicine · 2018
    3. Sirtuins pathways and redox homeostasis: a pilot study on young and old monozygotic twins Free Radical Biology and Medicine · 2015
    4. Acetate meliorates depressive-like behaviour in a rat model of PCOS through suppression of HDAC2 expression and DNA methylation Research Square (Research Square) · 2022 · 1 citations
    5. SIRT1 downregulation provokes immune-inflammatory responses in hair follicle outer root sheath cells and may contribute to development of alopecia areata Journal of Dermatological Science · 2023 · 13 citations
    6. Redox-directed interventions targeting skin photodamage Free Radical Biology and Medicine · 2015
    7. Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease Genes & Development · 2008 · 667 citations
    8. Epidermal Stem Cells Are Defined by Global Histone Modifications that Are Altered by Myc-Induced Differentiation PLoS ONE · 2007 · 98 citations
    9. Noval advance of histone modification in inflammatory skin diseases and related treatment methods Frontiers in immunology · 2024
    10. MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters Nature communications · 2023 · 1 citations
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