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    Did you mean Hedgehog signaling pathway?
    Glossary Hedgehog signaling pathway

    regulates cell growth and development through protein-receptor interactions

    The Hedgehog signaling pathway is a crucial mechanism in developmental biology that regulates cell growth, differentiation, and tissue patterning. It involves the Hedgehog proteins binding to receptors on cell surfaces, which then trigger a cascade of intracellular events that influence gene expression. This pathway is essential for proper embryonic development and, when dysregulated, can lead to conditions such as cancer and congenital disorders.

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    1. Hedgehog signalling in skin development and cancer Experimental Dermatology · 2006 · 190 citations
    2. MIM and Cortactin Antagonism Regulates Ciliogenesis and Hedgehog Signaling Developmental Cell · 2010 · 118 citations
    3. Modulation of Hair Growth with Small Molecule Agonists of the Hedgehog Signaling Pathway Journal of Investigative Dermatology · 2005 · 113 citations
    4. Roles of the Hedgehog Signaling Pathway in Epidermal and Hair Follicle Development, Homeostasis, and Cancer Journal of developmental biology · 2017 · 72 citations
    5. Hedgehog signaling maintains hair follicle stem cell phenotype in young and aged human skin Aging Cell · 2009 · 62 citations
    6. The E6/E7 oncogenes of human papilloma virus and estradiol regulate hedgehog signaling activity in a murine model of cervical cancer Experimental Cell Research · 2019 · 9 citations
    7. Hedgehog Signaling in Papillary Fibroblasts Is Essential for Hair Follicle Regeneration during Wound Healing Journal of Investigative Dermatology · 2021 · 5 citations
    8. Roles of the Hedgehog Signaling Pathway in Cutaneous Physiology and Oncology International journal of dermatology and venereology · 2019
    9. Disruption of the hedgehog signaling pathway contributes to the hair follicle cycling deficiency in Vdr knockout mice Journal of Cellular Physiology · 2010 · 53 citations
    10. Hedgehog Signaling, Keratin 6 Induction, and Sebaceous Gland Morphogenesis American Journal Of Pathology · 2008 · 33 citations
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